.dogma{--dogma-band:#fef3c7;--dogma-band-edge:#f59e0b;--dogma-pill:#ffffffd1;--dogma-A:#15803d;--dogma-C:#1d4ed8;--dogma-G:#a16207;--dogma-U:#7e22ce}@media (prefers-color-scheme:dark){.dogma{--dogma-band:#3a2f12;--dogma-band-edge:#b45309;--dogma-pill:#0f172ac7;--dogma-A:#4ade80;--dogma-C:#93c5fd;--dogma-G:#fde047;--dogma-U:#d8b4fe}}.dogma__intro{margin:0 0 .8rem;font-size:.95rem}.dogma__toggle{border:1px solid var(--border);border-radius:9px;margin-bottom:.75rem;display:inline-flex;overflow:hidden}.dogma__toggle button{font:inherit;background:var(--bg);color:var(--muted);cursor:pointer;border:0;padding:.5em 1.1em;font-size:.92rem}.dogma__toggle button+button{border-left:1px solid var(--border)}.dogma__toggle button.is-active{background:var(--accent);color:var(--accent-text);font-weight:600}.dogma__takeaway{border-left:4px solid var(--accent);background:var(--accent-soft);border-radius:0 9px 9px 0;margin:0 0 .9rem;padding:.55rem .85rem;font-weight:650;line-height:1.45}.dogma__steps{grid-template-columns:repeat(6,minmax(0,1fr));gap:.4rem;margin:0 0 .8rem;padding:0;list-style:none;display:grid}.dogma__steps li{min-width:0;margin:0}.dogma__step{text-align:center;border:1px solid var(--border);background:var(--bg);width:100%;height:100%;min-height:2.75rem;color:var(--text);font:inherit;cursor:pointer;border-radius:9px;flex-direction:column;justify-content:center;align-items:center;gap:.2rem;padding:.35rem .25rem;font-size:.84rem;font-weight:600;line-height:1.2;display:flex}.dogma__step:hover{border-color:var(--accent)}.dogma__step.is-selected{background:var(--accent-soft);border-color:var(--accent);box-shadow:0 0 0 1px var(--accent) inset}.dogma__step--all{color:var(--muted)}.dogma__step-n,.dogma__info-n{background:var(--surface-2);border:1px solid var(--border);font-variant-numeric:tabular-nums;border-radius:50%;flex:none;place-items:center;width:1.45rem;height:1.45rem;font-size:.78rem;font-weight:800;display:inline-grid}.dogma__step.is-selected .dogma__step-n{background:var(--accent);border-color:var(--accent);color:var(--accent-text)}.dogma__step-name{hyphens:auto;overflow-wrap:break-word;min-width:0;max-width:100%}.dogma__body{grid-template-columns:minmax(0,1.45fr) minmax(0,1fr);align-items:start;gap:1rem;display:grid}.dogma__art{background:radial-gradient(circle at 30% 20%, color-mix(in srgb, var(--accent) 7%, transparent), transparent 60%), var(--surface-2);border:1px solid var(--border);border-radius:10px;overflow:hidden}.dogma__svg{-webkit-tap-highlight-color:transparent;width:100%;height:auto;display:block}.dogma__p{transition:opacity .35s}.dogma__svg[data-step=gene] .dogma__p:not(.dogma__p--gene),.dogma__svg[data-step=transcription] .dogma__p:not(.dogma__p--transcription),.dogma__svg[data-step=mrna] .dogma__p:not(.dogma__p--mrna),.dogma__svg[data-step=translation] .dogma__p:not(.dogma__p--translation),.dogma__svg[data-step=protein] .dogma__p:not(.dogma__p--protein){opacity:.28}.dogma__halo{opacity:0;transition:opacity .35s}.dogma__halo-stop{stop-color:var(--accent)}.dogma__halo--gene{fill:color-mix(in srgb, var(--accent) 16%, transparent);stroke:var(--accent);stroke-width:3px;stroke-dasharray:10 7}.dogma__halo-path{fill:none;stroke:color-mix(in srgb, var(--accent) 28%, transparent);stroke-width:54px;stroke-linecap:round;stroke-linejoin:round}.dogma__svg[data-step=gene] .dogma__halo--gene,.dogma__svg[data-step=transcription] .dogma__halo--transcription,.dogma__svg[data-step=mrna] .dogma__halo--mrna,.dogma__svg[data-step=translation] .dogma__halo--translation,.dogma__svg[data-step=protein] .dogma__halo--protein{opacity:1}.dogma__gene-band{fill:var(--dogma-band);stroke:var(--dogma-band-edge);stroke-width:1.5px;stroke-opacity:.6}.dogma__promoter{fill:none;stroke:var(--text);stroke-width:4px;stroke-linejoin:round}.dogma__promoter-head{fill:var(--text)}.dogma__codon-pill{fill:var(--dogma-pill)}.dogma__base{font-family:var(--font-mono);text-anchor:middle;font-size:26px;font-weight:800}.dogma__base--A{fill:var(--dogma-A)}.dogma__base--C{fill:var(--dogma-C)}.dogma__base--G{fill:var(--dogma-G)}.dogma__base--U{fill:var(--dogma-U)}.dogma__end{fill:var(--text);font-size:26px;font-weight:800}.dogma__label{cursor:pointer}.dogma__label-text{fill:var(--text);paint-order:stroke;stroke:var(--surface-2);stroke-width:7px;stroke-linejoin:round;font-size:30px;font-weight:750}.dogma__label-sub,.dogma__note{fill:var(--muted);paint-order:stroke;stroke:var(--surface-2);stroke-width:6px;stroke-linejoin:round;font-size:26px;font-weight:600}.dogma__badge{fill:var(--surface);stroke:var(--text);stroke-width:2.5px}.dogma__badge-num{text-anchor:middle;fill:var(--text);font-size:22px;font-weight:800}.dogma__svg[data-step=gene] .dogma__p--gene .dogma__badge,.dogma__svg[data-step=transcription] .dogma__p--transcription .dogma__badge,.dogma__svg[data-step=mrna] .dogma__p--mrna .dogma__badge,.dogma__svg[data-step=translation] .dogma__p--translation .dogma__badge,.dogma__svg[data-step=protein] .dogma__p--protein .dogma__badge{fill:var(--accent);stroke:var(--accent)}.dogma__svg[data-step=gene] .dogma__p--gene .dogma__badge-num,.dogma__svg[data-step=transcription] .dogma__p--transcription .dogma__badge-num,.dogma__svg[data-step=mrna] .dogma__p--mrna .dogma__badge-num,.dogma__svg[data-step=translation] .dogma__p--translation .dogma__badge-num,.dogma__svg[data-step=protein] .dogma__p--protein .dogma__badge-num{fill:var(--accent-text)}.dogma__surface{opacity:.5}@media (prefers-color-scheme:dark){.dogma__surface{opacity:.38}}.dogma__svg[data-view=code] .dogma__read{display:none}.dogma__read-box{fill:var(--surface);stroke:var(--c-bio);stroke-width:2px}.dogma__read-title{fill:var(--c-bio);font-size:26px;font-weight:750}.dogma__read-label{fill:var(--muted);font-size:24px;font-weight:650}.dogma__read-letters{font-family:var(--font-mono);text-anchor:middle;font-size:36px;font-weight:800}.dogma__read-pair{stroke:var(--muted);stroke-width:2.5px;stroke-dasharray:3 3}.dogma__read-aa{text-anchor:middle;fill:var(--text);font-size:25px;font-weight:750}.dogma__svg[data-view=bio] .dogma__table{display:none}.dogma__table-box{fill:var(--surface);stroke:var(--c-swe);stroke-width:2px}.dogma__table-title{fill:var(--c-swe);font-size:26px;font-weight:750}.dogma__table-hit{fill:color-mix(in srgb, var(--c-swe) 18%, transparent)}.dogma__table-row{font-family:var(--font-mono);fill:var(--muted);font-size:25px}.dogma__table-row.is-current{fill:var(--text);font-weight:700}.dogma__hits>*{fill:#0000;cursor:pointer}.dogma__hits>.dogma__hit-stroke{fill:none;stroke:#0000;stroke-width:56px;pointer-events:stroke}.dogma__info{border:1px solid var(--border);background:var(--bg);border-radius:10px;padding:.8rem .9rem .85rem;scroll-margin-bottom:1rem}.dogma__info p{margin:0 0 .55rem}.dogma__info-title{flex-wrap:wrap;align-items:center;gap:.45rem;font-size:1.08rem;display:flex}.dogma__info-n{background:var(--accent);border-color:var(--accent);color:var(--accent-text)}.dogma__info-bio{color:var(--muted);font-size:.9rem}.dogma__badges{flex-wrap:wrap;gap:.35rem;display:flex}.dogma__badges .badge{font-size:.78rem}.dogma__nav{justify-content:space-between;gap:.5rem;margin-top:.4rem;display:flex}.dogma__key{color:var(--muted);flex-wrap:wrap;gap:.35rem 1.2rem;margin:.8rem 0 0;font-size:.85rem;display:flex}.dogma__key-item{flex-wrap:wrap;align-items:center;gap:.25rem;display:inline-flex}.dogma__swatch{border-radius:3px;width:.8rem;height:.8rem;margin-left:.15rem;display:inline-block}.dogma__swatch--round{border-radius:50%}.dogma__source{margin:.6rem 0 0;font-size:.8rem;line-height:1.5}@media (width<=760px){.dogma__body{grid-template-columns:minmax(0,1fr)}.dogma__art{width:100%;max-width:34rem;margin:0 auto}}@media (width<=640px){.dogma__steps{grid-template-columns:repeat(3,minmax(0,1fr))}.dogma__step{padding:.3rem .2rem;font-size:.82rem}.dogma__label-sub{display:none}.dogma__nav .button{flex:1 1 0;justify-content:center}}@media (pointer:coarse){.dogma__toggle button{min-height:44px}}.genome{--genome-faded:.13}.genome__arc--translation{--gc:#f97316}.genome__arc--rna{--gc:#a855f7}.genome__arc--dna{--gc:#6366f1}.genome__arc--transport{--gc:#06b6d4}.genome__arc--metabolism{--gc:#22c55e}.genome__arc--membrane{--gc:#eab308}.genome__arc--division{--gc:#ef4444}.genome__arc--unknown{--gc:#a3acb9}.genome__arc--rnagene{--gc:#1f2328}@media (prefers-color-scheme:dark){.genome__arc--unknown{--gc:#6b7684}.genome__arc--rnagene{--gc:#f1f5f9}.genome__arc--dna{--gc:#818cf8}}.genome__intro{margin:0 0 .8rem;font-size:.95rem}.genome__filters{flex-wrap:wrap;gap:.4rem;margin-bottom:.9rem;display:flex}.genome__filter{border:1px solid var(--border);background:var(--bg);min-height:2.5rem;color:var(--text);font:inherit;cursor:pointer;border-radius:999px;align-items:center;gap:.45rem;padding:.35rem .75rem;font-size:.88rem;font-weight:600;display:inline-flex}.genome__filter:hover{border-color:var(--accent)}.genome__filter.is-active{background:var(--accent);border-color:var(--accent);color:var(--accent-text)}.genome__filter-count{background:var(--surface-2);color:var(--muted);font-variant-numeric:tabular-nums;border-radius:999px;padding:.05em .5em;font-size:.78rem;font-weight:700}.genome__filter.is-active .genome__filter-count{background:color-mix(in srgb, var(--accent-text) 22%, transparent);color:var(--accent-text)}.genome__main{grid-template:"map nav""map find""map card"1fr"zoom zoom"/minmax(0,1.4fr) minmax(0,1fr);align-items:start;gap:.75rem 1.1rem;display:grid}.genome__map{grid-area:map}.genome__nav{grid-area:nav}.genome__find{grid-area:find}.genome__card{grid-area:card}.genome__zoom{grid-area:zoom}.genome__svg{cursor:pointer;-webkit-tap-highlight-color:transparent;width:100%;height:auto;display:block}.genome__track{fill:none;stroke:var(--surface-2)}.genome__backbone{fill:none;stroke:var(--muted);stroke-width:1.6px;opacity:.7}.genome__arc{fill:var(--gc);stroke:var(--gc);stroke-width:1.4px;stroke-linejoin:round;transition:opacity .3s}.genome__arc.is-faded,.genome__pin.is-faded{opacity:var(--genome-faded)}.genome__pin{fill:var(--text);stroke:var(--text);transition:opacity .3s}.genome__pin path{stroke-width:2px;fill:none}.genome__pin circle,.genome__pin rect{stroke:var(--surface);stroke-width:1.5px}.genome__rrna-label{fill:var(--text);text-anchor:middle;dominant-baseline:middle;font-size:32px;font-weight:700}.genome__svg[data-filter=protein] .genome__rrna-label,.genome__svg[data-filter=tga] .genome__rrna-label,.genome__svg[data-filter=unknown] .genome__rrna-label{opacity:var(--genome-faded)}.genome__svg.has-sel .genome__rrna-label{opacity:0}.genome__tick{stroke:var(--muted);stroke-width:1.5px}.genome__tick.is-major{stroke-width:2.5px}.genome__tick-label{fill:var(--muted);text-anchor:middle;dominant-baseline:middle;font-size:32px;font-weight:600}.genome__origin-line{stroke:var(--text);stroke-width:2px;stroke-dasharray:6 5}.genome__origin-mark{fill:var(--text)}.genome__origin-label{fill:var(--text);text-anchor:middle;font-size:32px;font-weight:750}.genome__window{fill:color-mix(in srgb, var(--accent) 12%, transparent);stroke:var(--accent);stroke-width:2px;stroke-dasharray:6 5}.genome__sel-arc{fill:none;stroke:var(--text);stroke-width:5px;stroke-linejoin:round}.genome__needle{stroke:var(--accent);stroke-width:5px;stroke-linecap:round}.genome__needle-dot{fill:var(--accent);stroke:var(--surface);stroke-width:2.5px}.genome__pointer{fill:var(--accent);stroke:var(--surface);stroke-width:2px}.genome__center{fill:var(--text);text-anchor:middle;pointer-events:none}.genome__c-small{fill:var(--muted);font-size:32px;font-weight:600}.genome__c-line{font-size:40px;font-weight:700}.genome__c-count{fill:var(--accent);font-variant-numeric:tabular-nums;font-size:118px;font-weight:800}.genome__c-name{font-weight:800}.genome__c-tag{font-family:var(--font-mono);fill:var(--muted);font-size:32px}.genome__c-loc{font-family:var(--font-mono);font-size:31px;font-weight:700}.genome__c-hint{fill:var(--accent);font-size:30px;font-weight:700}.genome__nav{justify-content:space-between;align-items:center;gap:.5rem;display:flex}.genome__nav-pos{color:var(--muted);font-variant-numeric:tabular-nums;text-align:center;font-size:.88rem}.genome__find-label{margin-bottom:.25rem;font-weight:600;display:block}.genome__find-row{gap:.4rem;display:flex}.genome__find input{min-width:0;font:inherit;border:1px solid var(--border);background:var(--bg);color:var(--text);border-radius:8px;flex:auto;padding:.45em .65em;font-size:.95rem}.genome__results{border:1px solid var(--border);border-radius:9px;margin:.4rem 0 0;padding:0;list-style:none;overflow:hidden}.genome__results li{margin:0}.genome__results li+li{border-top:1px solid var(--border)}.genome__results button{background:var(--bg);width:100%;min-height:2.75rem;color:var(--text);font:inherit;text-align:left;cursor:pointer;border:0;padding:.4rem .7rem;font-size:.9rem;display:block}.genome__results button:hover,.genome__results button:focus-visible{background:var(--accent-soft)}.genome__result-product{color:var(--muted);font-size:.8rem;line-height:1.3;display:block}.genome__no-result{padding:.5rem .7rem;font-size:.9rem}.genome__zoom-title{margin:0 0 .3rem;font-size:.92rem}.genome__strip{border:1px solid var(--border);background:var(--surface-2);border-radius:10px;overflow:hidden}.genome__strip-svg{cursor:pointer;-webkit-tap-highlight-color:transparent;width:100%;height:auto;display:block}.genome__grid{stroke:var(--border);stroke-width:1px}.genome__strip-kb{fill:var(--muted);text-anchor:middle;font-variant-numeric:tabular-nums;font-size:11px}.genome__axis{stroke:var(--muted);stroke-width:1.5px}.genome__strip-origin{stroke:var(--text);stroke-width:1.5px;stroke-dasharray:4 3}.genome__strip-origin-label{fill:var(--text);font-size:11px;font-weight:700}.genome__arrow{fill:var(--gc);stroke:var(--surface-2);stroke-width:1px;transition:opacity .3s}.genome__arrow.is-faded{opacity:.25}.genome__arrow.is-selected{stroke:var(--text);stroke-width:2.5px}.genome__strip-name{fill:var(--text);text-anchor:middle;font-size:12px;font-weight:600}.genome__strip-name.is-selected{font-size:13px;font-weight:800}.genome__zoom-note{margin:.3rem 0 0;font-size:.8rem}.genome__card{border:1px solid var(--border);background:var(--bg);border-radius:10px;padding:.75rem .9rem .8rem;scroll-margin-bottom:1rem}.genome__card p{margin:0 0 .5rem}.genome__card-title{flex-wrap:wrap;align-items:center;gap:.45rem;font-size:1.1rem;display:flex}.genome__also{color:var(--muted);font-size:.85rem}.genome__product{font-weight:600;line-height:1.4}.genome__dot{background:var(--gc);vertical-align:-.1em;border-radius:3px;flex:none;width:.85rem;height:.85rem;display:inline-block}.genome__facts{grid-template-columns:max-content minmax(0,1fr);gap:.25rem .75rem;margin:0 0 .5rem;font-size:.9rem;line-height:1.4;display:grid}.genome__facts dt{color:var(--muted);font-weight:600}.genome__facts dd{overflow-wrap:anywhere;margin:0}.genome__facts .muted{font-size:.85em}.genome__index{font-size:.8rem}.genome__legend{border-top:1px solid var(--border);margin-top:.9rem;padding-top:.7rem}.genome__legend-title{margin:0 0 .35rem;font-size:.9rem;font-weight:600}.genome__legend ul{flex-wrap:wrap;gap:.3rem 1rem;margin:0;padding:0;font-size:.86rem;list-style:none;display:flex}.genome__legend li{align-items:center;gap:.35rem;margin:0;display:inline-flex}.genome__pins-key svg{display:block}.genome__key-shape{fill:var(--text)}.genome__legend-note{margin:.5rem 0 0;font-size:.8rem;line-height:1.5}.genome__source{margin:.4rem 0 0;font-size:.8rem}@media (width<=760px){.genome__main{grid-template-rows:none;grid-template-columns:minmax(0,1fr);grid-template-areas:"map""nav""find""zoom""card"}.genome__map{justify-self:center;width:100%;max-width:32rem}}@media (width<=640px){.genome__map{width:calc(100% + 1rem);max-width:none;margin:0 -.5rem}.genome__filter{flex:auto;justify-content:center}.genome__facts{grid-template-columns:minmax(0,1fr);gap:.05rem}.genome__facts dd{margin-bottom:.35rem}}@media (pointer:coarse){.genome__filter{min-height:44px}.genome__find .button,.genome__nav .button{min-width:44px}}.codon{--codon-heat:#0f766e;--codon-heat-text:#fff;--codon-veil:#ffffff80;--codon-t-A:#15803d;--codon-t-C:#1d4ed8;--codon-t-G:#a16207;--codon-t-U:#7e22ce}@media (prefers-color-scheme:dark){.codon{--codon-heat:#2dd4bf;--codon-heat-text:#04201d;--codon-veil:#0e13158c;--codon-t-A:#4ade80;--codon-t-C:#93c5fd;--codon-t-G:#fde047;--codon-t-U:#d8b4fe}}.codon__b--U{--bc:#a855f7}.codon__b--C{--bc:#3b82f6}.codon__b--A{--bc:#22c55e}.codon__b--G{--bc:#eab308}.codon__k--oily{--kc:#f59e0b}.codon__k--polar{--kc:#38bdf8}.codon__k--plus{--kc:#818cf8}.codon__k--minus{--kc:#fb7185}.codon__k--special{--kc:#cbd5e1}.codon__k--stop{--kc:#334155}.codon__intro{margin:0 0 .8rem;font-size:.95rem}.codon__controls{flex-wrap:wrap;align-items:center;gap:.5rem .75rem;margin-bottom:.75rem;display:flex}.codon__toggle{border:1px solid var(--border);border-radius:9px;display:inline-flex;overflow:hidden}.codon__toggle button{font:inherit;background:var(--bg);color:var(--muted);cursor:pointer;border:0;padding:.5em 1em;font-size:.92rem}.codon__toggle button+button{border-left:1px solid var(--border)}.codon__toggle button.is-active{background:var(--accent);color:var(--accent-text);font-weight:600}.codon__switch{font:inherit;border:1px solid var(--border);background:var(--bg);color:var(--text);cursor:pointer;border-radius:999px;align-items:center;gap:.5rem;padding:.45em .85em .45em .5em;font-size:.9rem;font-weight:600;display:inline-flex}.codon__switch:hover{border-color:var(--accent)}.codon__switch-knob{background:var(--border);border-radius:999px;width:2.1rem;height:1.2rem;transition:background-color .2s;position:relative}.codon__switch-knob:after{content:"";background:var(--surface);border-radius:50%;width:.9rem;height:.9rem;transition:transform .2s;position:absolute;top:.15rem;left:.15rem;box-shadow:0 1px 2px #0000004d}.codon__switch.is-on .codon__switch-knob{background:var(--accent)}.codon__switch.is-on .codon__switch-knob:after{transform:translate(.9rem)}.codon__takeaway{border-left:4px solid var(--accent);background:var(--accent-soft);border-radius:0 9px 9px 0;margin:0 0 .9rem;padding:.55rem .85rem;font-weight:650;line-height:1.45}.codon__main{grid-template-columns:minmax(0,1.4fr) minmax(0,1fr);align-items:start;gap:1rem;display:grid}.codon__side{flex-direction:column;gap:.8rem;min-width:0;display:flex}.codon__svg{cursor:pointer;-webkit-tap-highlight-color:transparent;width:100%;height:auto;display:block}.codon__r1{fill:var(--bc);stroke:var(--surface);stroke-width:3px}.codon__r2{fill:color-mix(in srgb, var(--bc) 58%, var(--surface));stroke:var(--surface);stroke-width:2.5px}.codon__r3{fill:color-mix(in srgb, var(--bc) 30%, var(--surface));stroke:var(--surface);stroke-width:1.5px;transition:fill .4s}.codon__r3.is-heat{fill:color-mix(in srgb, var(--codon-heat) var(--heat), var(--surface))}.codon__l1{fill:#fff;text-anchor:middle;dominant-baseline:central;paint-order:stroke;stroke:#0f172a59;stroke-width:5px;font-size:64px;font-weight:800}.codon__l2{fill:var(--text);text-anchor:middle;dominant-baseline:central;pointer-events:none;font-size:44px;font-weight:800}.codon__l3{fill:var(--text);text-anchor:middle;dominant-baseline:central;pointer-events:none;font-size:31px;font-weight:750;transition:fill .4s}.codon__l3.is-hot{fill:var(--codon-heat-text)}.codon__w{stroke:var(--surface);stroke-width:.8px;transition:fill .6s}.codon__w--oily{fill:color-mix(in srgb, #f59e0b 55%, var(--surface))}.codon__w--polar{fill:color-mix(in srgb, #38bdf8 55%, var(--surface))}.codon__w--plus{fill:color-mix(in srgb, #818cf8 55%, var(--surface))}.codon__w--minus{fill:color-mix(in srgb, #fb7185 55%, var(--surface))}.codon__w--special{fill:color-mix(in srgb, #cbd5e1 65%, var(--surface))}.codon__w--stop{fill:#334155}@media (prefers-color-scheme:dark){.codon__w--oily{fill:color-mix(in srgb, #f59e0b 66%, var(--surface))}.codon__w--polar{fill:color-mix(in srgb, #38bdf8 62%, var(--surface))}.codon__w--plus{fill:color-mix(in srgb, #818cf8 66%, var(--surface))}.codon__w--minus{fill:color-mix(in srgb, #fb7185 62%, var(--surface))}.codon__w--special{fill:color-mix(in srgb, #cbd5e1 52%, var(--surface))}.codon__w--stop{fill:#0b1013}.codon__aa1,.codon__aa3{fill:#fff;paint-order:stroke;stroke:#00000059;stroke-width:4px}.codon__r3{fill:color-mix(in srgb, var(--bc) 40%, var(--surface))}}.codon__div{stroke:var(--surface);stroke-width:3.5px;transition:opacity .6s}.codon__label{pointer-events:none;transition:opacity .6s}.codon__svg[data-code=standard] .codon__for--syn3a,.codon__svg[data-code=syn3a] .codon__for--standard{opacity:0}.codon__aa1{fill:var(--text);text-anchor:middle;dominant-baseline:central;font-size:34px;font-weight:800}.codon__aa3{fill:var(--text);dominant-baseline:central;font-size:32px;font-weight:650}.codon__label.is-stop .codon__aa3{fill:#fff;font-weight:750}.codon__octagon{fill:#dc2626;stroke:#fff;stroke-width:2.5px}.codon__start path{fill:#15803d;stroke:#fff;stroke-width:2px}.codon__veil{fill:var(--codon-veil);pointer-events:none}.codon__outline{fill:none;stroke:var(--text);stroke-width:4.5px;stroke-linejoin:round;pointer-events:none}.codon__edge{fill:none;stroke:var(--border);stroke-width:2px;pointer-events:none}.codon__burst{fill:none;stroke:var(--accent);stroke-width:8px;pointer-events:none;transform-box:fill-box;transform-origin:50%;animation:1.1s ease-out forwards codon-burst}@keyframes codon-burst{0%{opacity:1;transform:scale(1)}to{opacity:0;transform:scale(1.9)}}@media (prefers-reduced-motion:reduce){.codon__burst{display:none}.codon__w,.codon__r3,.codon__div,.codon__label{transition:none}}.codon__builder{border:1px solid var(--border);background:var(--bg);border-radius:10px;padding:.6rem .75rem .7rem}.codon__builder-title{color:var(--muted);margin:0 0 .35rem;font-size:.88rem;font-weight:600}.codon__builder-row{grid-template-columns:2.4rem repeat(4,minmax(0,1fr));align-items:center;gap:.35rem;display:grid}.codon__builder-row+.codon__builder-row{margin-top:.35rem}.codon__builder-label{color:var(--muted);font-size:.8rem;font-weight:700}.codon__base-btn{border:1px solid color-mix(in srgb, var(--bc) 55%, transparent);background:color-mix(in srgb, var(--bc) 16%, var(--bg));min-height:2.5rem;color:var(--text);font:inherit;font-family:var(--font-mono);cursor:pointer;border-radius:8px;font-size:1.05rem;font-weight:800}.codon__base-btn:hover{background:color-mix(in srgb, var(--bc) 30%, var(--bg))}.codon__base-btn.is-on{background:var(--bc);border-color:var(--bc);color:#fff;text-shadow:0 1px 2px #00000059}.codon__answer{justify-content:center;width:100%;margin-top:.55rem}.codon__card{border:1px solid var(--border);background:var(--bg);border-radius:10px;padding:.75rem .9rem .8rem;scroll-margin-bottom:1rem}.codon__card p{margin:0 0 .5rem}.codon__card-head{flex-wrap:wrap;align-items:center;gap:.5rem;margin-bottom:.5rem;display:flex}.codon__tiles{gap:3px;display:inline-flex}.codon__tile{background:var(--bc);color:#fff;width:2.1rem;height:2.3rem;font-family:var(--font-mono);text-shadow:0 1px 2px #00000059;border-radius:7px;place-items:center;font-size:1.35rem;font-weight:800;display:inline-grid}.codon__arrow{color:var(--muted);font-size:1.3rem}.codon__aa-chip{background:color-mix(in srgb, var(--kc) 55%, var(--surface));border:2px solid var(--kc);border-radius:999px;align-items:center;min-height:2.3rem;padding:0 .8rem;font-size:1.05rem;font-weight:800;display:inline-flex}.codon__k--stop.codon__aa-chip{color:#fff;background:#334155;border-color:#dc2626}.codon__aa-chip--big{font-size:1.2rem}.codon__card-title{font-size:1.05rem;line-height:1.35}.codon__small{font-size:.88rem;line-height:1.5}.codon__note{border-left:3px solid var(--c-bio);background:var(--surface-2);border-radius:0 7px 7px 0;padding:.45rem .65rem;font-size:.9rem;line-height:1.5}.codon__usage-title{font-size:.9rem;margin-top:.6rem!important}.codon__bars{margin:0;padding:0;font-size:.86rem;list-style:none}.codon__bars li{border-radius:6px;grid-template-columns:3.1rem minmax(0,1fr) auto;align-items:center;gap:.5rem;margin:0;padding:.12rem .3rem;display:grid}.codon__bars li.is-current{background:var(--accent-soft);font-weight:700}.codon__bar-codon{font-family:var(--font-mono);letter-spacing:.04em;font-weight:800}.codon__t--A{color:var(--codon-t-A)}.codon__t--C{color:var(--codon-t-C)}.codon__t--G{color:var(--codon-t-G)}.codon__t--U{color:var(--codon-t-U)}.codon__bar-track{background:var(--surface-2);border-radius:999px;height:.7rem;overflow:hidden}.codon__bar{background:var(--codon-heat);border-radius:999px;height:100%;display:block}.codon__bar-num{font-variant-numeric:tabular-nums;text-align:right;white-space:nowrap}.codon__quiz-head{flex-wrap:wrap;justify-content:space-between;align-items:center;gap:.4rem;margin-bottom:.5rem;display:flex}.codon__quiz-count{color:var(--muted);font-size:.85rem;font-weight:600}.codon .game__sound{font:inherit;border:1px solid var(--border);background:var(--surface);color:var(--accent);cursor:pointer;border-radius:999px;align-items:center;gap:.35em;padding:.3em .7em;font-size:.8rem;font-weight:600;display:inline-flex}.codon .game__sound.is-off{color:var(--muted)}.codon__quiz-ask{font-size:1.1rem;line-height:1.4}.codon__feedback{border-radius:8px;padding:.45rem .65rem;font-size:.92rem;font-weight:600}.codon__feedback.is-ok{background:var(--success-soft);color:var(--success)}.codon__feedback.is-bad{background:var(--danger-soft);color:var(--danger)}.codon__stars{letter-spacing:.15em;color:var(--border);font-size:2rem;margin:0 0 .3rem!important}.codon__stars .is-on{color:#f59e0b}.codon__legend{color:var(--muted);flex-wrap:wrap;gap:.3rem 1rem;margin-top:.9rem;font-size:.85rem;display:flex}.codon__legend-item{align-items:center;gap:.35rem;display:inline-flex}.codon__swatch{border-radius:3px;width:.85rem;height:.85rem;display:inline-block}.codon__swatch--stop{background:#334155;box-shadow:inset 0 0 0 2px #dc2626}.codon__swatch--start{border-top:.45rem solid #0000;border-bottom:.45rem solid #0000;border-left:.8rem solid #15803d;border-radius:0;width:0;height:0}.codon__heat-key{font-variant-numeric:tabular-nums;flex-wrap:wrap;align-items:center;gap:.4rem .6rem;margin-top:.5rem;font-size:.85rem;display:flex}.codon__heat-bar{background:linear-gradient(90deg, color-mix(in srgb, var(--codon-heat) 8%, var(--surface)), var(--codon-heat));border:1px solid var(--border);border-radius:999px;width:7rem;height:.7rem}.codon__source{margin:.6rem 0 0;font-size:.8rem;line-height:1.5}@media (width<=760px){.codon__main{grid-template-columns:minmax(0,1fr)}.codon__wheel{justify-self:center;width:100%;max-width:32rem}}@media (width<=640px){.codon__wheel{width:calc(100% + 1rem);max-width:none;margin:0 -.5rem}.codon__toggle{width:100%}.codon__toggle button{flex:1 1 0}.codon__switch{flex:auto;justify-content:center}}@media (pointer:coarse){.codon__toggle button,.codon__switch,.codon__base-btn,.codon .game__sound{min-height:44px}}.ga__defs[data-astro-cid-qhf25prv]{width:0;height:0;position:absolute;overflow:hidden}.ga[data-astro-cid-qhf25prv]{--ga-line:#475569;--ga-guide:#94a3b8;--ga-hatch-bg:#f472b614;--ga-hatch-line:#be185d59;--ga-rna:#f9a8d4;--ga-rna-edge:#be185d;--ga-rna-text:#be185d;--ga-fwd-text:#0f766e;--ga-rev-text:#6d28d9;--ga-promoter:#ea580c;--ga-sd:#a16207;--ga-start:#15803d;--ga-stop:#dc2626;--ga-gap:var(--surface);flex-wrap:wrap;justify-content:center;gap:1rem;margin:.4rem 0 1.4rem;display:flex}@media (prefers-color-scheme:dark){.ga[data-astro-cid-qhf25prv]{--ga-line:#cbd5e1;--ga-guide:#64748b;--ga-hatch-bg:#f472b60f;--ga-hatch-line:#f9a8d466;--ga-rna-edge:#f472b6;--ga-rna-text:#f9a8d4;--ga-fwd-text:#5eead4;--ga-rev-text:#c4b5fd;--ga-promoter:#fb923c;--ga-sd:#facc15;--ga-start:#4ade80;--ga-stop:#f87171}}.ga__fig[data-astro-cid-qhf25prv]{background:var(--surface);border:1px solid var(--border);border-top:4px solid var(--ga-accent);border-radius:var(--radius);flex:20rem;max-width:24rem;margin:0;padding:.6rem .65rem .75rem}.ga__name[data-astro-cid-qhf25prv]{letter-spacing:.08em;text-transform:uppercase;color:var(--ga-accent);margin:0 0 .3rem;font-size:.8rem;font-weight:700}svg[data-astro-cid-qhf25prv]:not(.ga__defs){width:100%;height:auto;display:block;overflow:visible}figcaption[data-astro-cid-qhf25prv]{margin-top:.45rem;font-size:.88rem;line-height:1.5}.ga__label[data-astro-cid-qhf25prv]{fill:var(--text);font-size:14px}.ga__label--strong[data-astro-cid-qhf25prv]{font-weight:700}.ga__label--rna[data-astro-cid-qhf25prv]{fill:var(--ga-rna-text);font-size:15px;font-weight:800}.ga__label--fwd[data-astro-cid-qhf25prv]{fill:var(--ga-fwd-text);font-weight:700}.ga__label--rev[data-astro-cid-qhf25prv]{fill:var(--ga-rev-text);font-weight:700}.ga__small[data-astro-cid-qhf25prv]{fill:var(--text);font-size:13px}.ga__small--muted[data-astro-cid-qhf25prv]{fill:var(--muted)}.ga__seq[data-astro-cid-qhf25prv]{font-family:var(--font-mono);letter-spacing:.02em;font-size:13px;font-weight:700}.ga__seq--promoter[data-astro-cid-qhf25prv]{fill:var(--ga-promoter)}.ga__seq--sd[data-astro-cid-qhf25prv]{fill:var(--ga-sd)}.ga__seq--start[data-astro-cid-qhf25prv]{fill:var(--ga-start)}.ga__seq--stop[data-astro-cid-qhf25prv]{fill:var(--ga-stop)}.ga__code[data-astro-cid-qhf25prv]{fill:var(--text);font-family:var(--font-mono);font-size:12.5px}.ga__end[data-astro-cid-qhf25prv]{fill:var(--muted);font-size:13px;font-weight:700}.ga__end--small[data-astro-cid-qhf25prv]{font-size:12.5px}.ga__tick-label[data-astro-cid-qhf25prv]{fill:var(--muted);font-size:12.5px}.ga__bracket[data-astro-cid-qhf25prv],.ga__leader[data-astro-cid-qhf25prv],.ga__dim[data-astro-cid-qhf25prv]{fill:none;stroke:var(--ga-line);stroke-width:1.4px;stroke-linejoin:round}.ga__bracket--strong[data-astro-cid-qhf25prv]{stroke-width:2.2px}.ga__leader[data-astro-cid-qhf25prv]{stroke:var(--muted);stroke-dasharray:2 2}.ga__arrowhead[data-astro-cid-qhf25prv]{fill:var(--ga-line)}.ga__arrowhead--ink[data-astro-cid-qhf25prv]{fill:var(--text)}.ga__arrowhead--violet[data-astro-cid-qhf25prv]{fill:#7c3aed}.ga__arrowhead--stop[data-astro-cid-qhf25prv]{fill:var(--ga-stop)}.ga__arrowhead--start[data-astro-cid-qhf25prv]{fill:var(--ga-start)}.ga__arrowhead--rev[data-astro-cid-qhf25prv]{fill:var(--ga-rev-text)}.ga__bent[data-astro-cid-qhf25prv]{fill:none;stroke:var(--text);stroke-width:2.4px;stroke-linejoin:round}.ga__repeat[data-astro-cid-qhf25prv]{fill:none;stroke:#7c3aed;stroke-width:2px}.ga__guide[data-astro-cid-qhf25prv]{fill:none;stroke:var(--ga-guide);stroke-width:1.3px;stroke-dasharray:3 3}.ga__rail[data-astro-cid-qhf25prv]{stroke:#0f172a40;stroke-width:.6px}.ga__band[data-astro-cid-qhf25prv]{stroke-width:1.2px}.ga__rung--muted[data-astro-cid-qhf25prv]{opacity:.32}.ga__band--promoter[data-astro-cid-qhf25prv]{fill:#fb923c47;stroke:#ea580cb3}.ga__band--sd[data-astro-cid-qhf25prv]{fill:#fde04759;stroke:#ca8a04bf}.ga__band--start[data-astro-cid-qhf25prv]{fill:#4ade804d;stroke:#16a34acc}.ga__band--codon[data-astro-cid-qhf25prv]{fill:#94a3b847;stroke:#64748b8c}.ga__band--codon2[data-astro-cid-qhf25prv]{fill:#94a3b81f;stroke:#64748b8c}.ga__band--stop[data-astro-cid-qhf25prv]{fill:#f871714d;stroke:#dc2626cc}.ga__band--term[data-astro-cid-qhf25prv]{fill:#a78bfa40;stroke:#7c3aedb3}.ga__gap[data-astro-cid-qhf25prv]{fill:var(--ga-gap)}.ga__gap-line[data-astro-cid-qhf25prv]{fill:none;stroke:var(--ga-line);stroke-width:1.4px}.ga__rna[data-astro-cid-qhf25prv],.ga__rna-edge[data-astro-cid-qhf25prv]{fill:none;stroke-linecap:round;stroke-linejoin:round}.ga__rna[data-astro-cid-qhf25prv]{stroke:var(--ga-rna);stroke-width:4.5px}.ga__rna-edge[data-astro-cid-qhf25prv]{stroke:var(--ga-rna-edge);stroke-width:6.5px}.ga__hatch-bg[data-astro-cid-qhf25prv]{fill:var(--ga-hatch-bg)}.ga__hatch-line[data-astro-cid-qhf25prv]{stroke:var(--ga-hatch-line);stroke-width:1.6px}.ga__strand[data-astro-cid-qhf25prv]{stroke-width:3px;stroke-linecap:round}.ga__strand--fwd[data-astro-cid-qhf25prv]{stroke:#f0c27a}.ga__strand--rev[data-astro-cid-qhf25prv]{stroke:#7dd3fc}.ga__tick[data-astro-cid-qhf25prv]{stroke:var(--muted);stroke-width:1px}.ga__gene[data-astro-cid-qhf25prv]{stroke:#0f172a66;stroke-width:.8px;stroke-linejoin:round}.ga__gene-label[data-astro-cid-qhf25prv]{fill:#fff;paint-order:stroke;stroke:#0f172a73;stroke-width:2.4px;stroke-linejoin:round;font-size:13px;font-weight:800}.ga__start-mark[data-astro-cid-qhf25prv]{fill:#22c55e;stroke:#14532d;stroke-width:.6px}.ga__lollipop[data-astro-cid-qhf25prv]{stroke:#7c3aed;stroke-width:2px}.ga__lollipop-head[data-astro-cid-qhf25prv]{fill:#c4b5fd;stroke:#7c3aed;stroke-width:1.6px}.ga__tile[data-astro-cid-qhf25prv]{stroke:#0f172a4d;stroke-width:.8px}.ga__tile--faded[data-astro-cid-qhf25prv]{opacity:.5}.ga__tile-letter[data-astro-cid-qhf25prv]{font-family:var(--font-mono);pointer-events:none;font-size:14px;font-weight:800}.ga__read[data-astro-cid-qhf25prv]{fill:none;stroke-width:3px;stroke-linecap:round}.ga__read--stop[data-astro-cid-qhf25prv]{stroke:var(--ga-stop)}.ga__read--start[data-astro-cid-qhf25prv]{stroke:var(--ga-start)}.ga__big-arrow[data-astro-cid-qhf25prv]{fill:none;stroke:var(--ga-rev-text);stroke-width:3px;stroke-linecap:round}@media (width<=420px){.ga__fig[data-astro-cid-qhf25prv]{padding:.5rem .45rem .65rem}}.tf__defs[data-astro-cid-ehbraoxv]{width:0;height:0;position:absolute;overflow:hidden}.tf[data-astro-cid-ehbraoxv]{--tf-line:#475569;--tf-rna:#f9a8d4;--tf-rna-edge:#be185d;--tf-rna-text:#be185d;--tf-template-text:#0369a1;--tf-box-text:#c2410c;--tf-halo:var(--surface);--tf-hybrid:#fde04747;flex-wrap:wrap;justify-content:center;gap:1rem;margin:.4rem 0 1.4rem;display:flex}@media (prefers-color-scheme:dark){.tf[data-astro-cid-ehbraoxv]{--tf-line:#cbd5e1;--tf-rna-edge:#f472b6;--tf-rna-text:#f9a8d4;--tf-template-text:#7dd3fc;--tf-box-text:#fb923c;--tf-hybrid:#fde0474d}}.tf__fig[data-astro-cid-ehbraoxv]{background:var(--surface);border:1px solid var(--border);border-top:4px solid var(--tf-accent);border-radius:var(--radius);flex:20rem;max-width:24rem;margin:0;padding:.6rem .65rem .75rem}.tf__name[data-astro-cid-ehbraoxv]{letter-spacing:.08em;text-transform:uppercase;color:var(--tf-accent);margin:0 0 .3rem;font-size:.8rem;font-weight:700}svg[data-astro-cid-ehbraoxv]:not(.tf__defs){width:100%;height:auto;display:block;overflow:visible}figcaption[data-astro-cid-ehbraoxv]{margin-top:.45rem;font-size:.88rem;line-height:1.5}.tf__label[data-astro-cid-ehbraoxv]{fill:var(--text);font-size:14px}.tf__label--strong[data-astro-cid-ehbraoxv]{font-weight:700}.tf__label--rna[data-astro-cid-ehbraoxv]{fill:var(--tf-rna-text);font-size:15px;font-weight:800}.tf__label--template[data-astro-cid-ehbraoxv]{fill:var(--tf-template-text);font-weight:700}.tf__small[data-astro-cid-ehbraoxv]{fill:var(--text);font-size:13px}.tf__small--muted[data-astro-cid-ehbraoxv]{fill:var(--muted)}.tf__small--strong[data-astro-cid-ehbraoxv]{font-weight:700}.tf__seq[data-astro-cid-ehbraoxv]{font-family:var(--font-mono);font-size:13px;font-weight:700}.tf__seq--box[data-astro-cid-ehbraoxv]{fill:var(--tf-box-text)}.tf__end[data-astro-cid-ehbraoxv]{fill:var(--muted);font-size:13px;font-weight:700}.tf__end--rna[data-astro-cid-ehbraoxv]{fill:var(--tf-rna-text);font-size:14px;font-weight:800}.tf__on-enzyme[data-astro-cid-ehbraoxv]{fill:#1e1b4b;paint-order:stroke;stroke:#eef2ffd9;stroke-width:3px;stroke-linejoin:round;font-size:14px;font-weight:800}.tf__on-enzyme--small[data-astro-cid-ehbraoxv]{font-size:13px;font-weight:700}.tf__on-enzyme--coding[data-astro-cid-ehbraoxv]{fill:#7c4a03}.tf__on-sigma[data-astro-cid-ehbraoxv]{fill:#431407;paint-order:stroke;stroke:#ffedd5b3;stroke-width:2.5px;font-size:13px;font-weight:800}.tf__letter[data-astro-cid-ehbraoxv]{font-family:var(--font-mono);pointer-events:none;font-size:13px;font-weight:800}.tf__rail[data-astro-cid-ehbraoxv]{stroke:#0f172a40;stroke-width:.6px}.tf__box[data-astro-cid-ehbraoxv]{fill:#fb923c47;stroke:#ea580cbf;stroke-width:1.3px}.tf__core[data-astro-cid-ehbraoxv]{stroke:#4338ca;stroke-width:1.6px}.tf__core--open[data-astro-cid-ehbraoxv]{stroke-opacity:.8}.tf__alpha[data-astro-cid-ehbraoxv]{stroke:#334155;stroke-width:1.2px}.tf__channel[data-astro-cid-ehbraoxv]{fill:#312e81;opacity:.55}.tf__channel--open[data-astro-cid-ehbraoxv]{opacity:.32}.tf__shine[data-astro-cid-ehbraoxv]{fill:#fff;opacity:.28}.tf__sigma[data-astro-cid-ehbraoxv]{stroke:#9a3412;stroke-width:1.4px}.tf__sigma-linker[data-astro-cid-ehbraoxv]{fill:none;stroke:#ea580c;stroke-width:5px;stroke-linecap:round}.tf__label--sigma[data-astro-cid-ehbraoxv]{fill:var(--tf-box-text);font-weight:800}.tf__small--halo[data-astro-cid-ehbraoxv]{paint-order:stroke;stroke:var(--surface);stroke-width:3px}.tf__strand[data-astro-cid-ehbraoxv],.tf__strand-edge[data-astro-cid-ehbraoxv]{fill:none;stroke-linecap:round;stroke-linejoin:round}.tf__strand[data-astro-cid-ehbraoxv]{stroke-width:4px}.tf__strand-edge[data-astro-cid-ehbraoxv]{stroke:#0f172a59;stroke-width:6px}.tf__strand--coding[data-astro-cid-ehbraoxv]{stroke:#f0c27a}.tf__strand--template[data-astro-cid-ehbraoxv]{stroke:#7dd3fc}.tf__rna[data-astro-cid-ehbraoxv],.tf__rna-edge[data-astro-cid-ehbraoxv],.tf__rna-halo[data-astro-cid-ehbraoxv]{fill:none;stroke-linecap:round;stroke-linejoin:round}.tf__rna[data-astro-cid-ehbraoxv]{stroke:var(--tf-rna);stroke-width:4.5px}.tf__rna-edge[data-astro-cid-ehbraoxv]{stroke:var(--tf-rna-edge);stroke-width:6.5px}.tf__rna-halo[data-astro-cid-ehbraoxv]{stroke:#eef2ff;stroke-width:11px}.tf__tile[data-astro-cid-ehbraoxv]{stroke:#0f172a59;stroke-width:.8px}.tf__tile--rna[data-astro-cid-ehbraoxv]{stroke:#9d174d;stroke-width:1.4px}.tf__tile--next[data-astro-cid-ehbraoxv]{stroke:#ca8a04;stroke-width:2.4px}.tf__pair[data-astro-cid-ehbraoxv]{stroke:#475569;stroke-width:1.4px}.tf__hybrid[data-astro-cid-ehbraoxv]{fill:none;stroke:var(--tf-hybrid);stroke-width:46px;stroke-linecap:round;stroke-linejoin:round}.tf__term[data-astro-cid-ehbraoxv]{fill:#a78bfa38;stroke:#7c3aed99;stroke-width:1.2px}.tf__trun[data-astro-cid-ehbraoxv]{fill:#ef444429;stroke:#dc26268c;stroke-width:1.2px}.tf__repeat[data-astro-cid-ehbraoxv]{fill:none;stroke:#7c3aed;stroke-width:2px}.tf__bond[data-astro-cid-ehbraoxv]{stroke:#64748b;stroke-width:1.5px}.tf__bond--gc[data-astro-cid-ehbraoxv]{stroke:#475569}.tf__bracket[data-astro-cid-ehbraoxv],.tf__dim[data-astro-cid-ehbraoxv]{fill:none;stroke:var(--tf-line);stroke-width:1.4px}.tf__bent[data-astro-cid-ehbraoxv]{fill:none;stroke:var(--text);stroke-width:2.4px;stroke-linejoin:round}.tf__move[data-astro-cid-ehbraoxv]{fill:none;stroke:#6366f1;stroke-width:3px;stroke-linecap:round}.tf__motion[data-astro-cid-ehbraoxv]{fill:none;stroke:var(--muted);stroke-width:2px;stroke-linecap:round}.tf__motion--faint[data-astro-cid-ehbraoxv]{opacity:.5;stroke-dasharray:3 4}.tf__arrowhead[data-astro-cid-ehbraoxv]{fill:var(--tf-line)}.tf__arrowhead--ink[data-astro-cid-ehbraoxv]{fill:var(--text)}.tf__arrowhead--move[data-astro-cid-ehbraoxv]{fill:#6366f1}.tf__arrowhead--violet[data-astro-cid-ehbraoxv]{fill:#7c3aed}@media (prefers-color-scheme:dark){.tf__bond[data-astro-cid-ehbraoxv],.tf__bond--gc[data-astro-cid-ehbraoxv]{stroke:#cbd5e1}}@media (width<=420px){.tf__fig[data-astro-cid-ehbraoxv]{padding:.5rem .45rem .65rem}}.rf__defs[data-astro-cid-fxsylqpx]{width:0;height:0;position:absolute;overflow:hidden}.rf[data-astro-cid-fxsylqpx]{--rf-line:#475569;--rf-rna:#f9a8d4;--rf-rna-edge:#be185d;--rf-rrna:#fdba74;--rf-rrna-edge:#c2410c;--rf-rrna-text:#c2410c;--rf-sky-text:#0369a1;--rf-start:#15803d;--rf-stop:#dc2626;--rf-ghost:#0284c7;flex-wrap:wrap;justify-content:center;gap:1rem;margin:.4rem 0 1.4rem;display:flex}@media (prefers-color-scheme:dark){.rf[data-astro-cid-fxsylqpx]{--rf-line:#cbd5e1;--rf-rna-edge:#f472b6;--rf-rrna-text:#fdba74;--rf-sky-text:#7dd3fc;--rf-start:#4ade80;--rf-stop:#f87171;--rf-ghost:#7dd3fc}}.rf__fig[data-astro-cid-fxsylqpx]{background:var(--surface);border:1px solid var(--border);border-top:4px solid var(--rf-accent);border-radius:var(--radius);flex:20rem;max-width:24rem;margin:0;padding:.6rem .65rem .75rem}.rf__name[data-astro-cid-fxsylqpx]{letter-spacing:.08em;text-transform:uppercase;color:var(--rf-accent);margin:0 0 .3rem;font-size:.8rem;font-weight:700}svg[data-astro-cid-fxsylqpx]:not(.rf__defs){width:100%;height:auto;display:block;overflow:visible}figcaption[data-astro-cid-fxsylqpx]{margin-top:.45rem;font-size:.88rem;line-height:1.5}.rf__label[data-astro-cid-fxsylqpx]{fill:var(--text);font-size:14px}.rf__label--strong[data-astro-cid-fxsylqpx]{font-weight:700}.rf__label--sky[data-astro-cid-fxsylqpx]{fill:var(--rf-sky-text);font-weight:700}.rf__label--rrna[data-astro-cid-fxsylqpx]{fill:var(--rf-rrna-text);font-weight:800}.rf__small[data-astro-cid-fxsylqpx]{fill:var(--text);font-size:13px}.rf__small--muted[data-astro-cid-fxsylqpx]{fill:var(--muted)}.rf__small--strong[data-astro-cid-fxsylqpx]{font-weight:700}.rf__small--sky[data-astro-cid-fxsylqpx]{fill:var(--rf-sky-text)}.rf__small--halo[data-astro-cid-fxsylqpx]{paint-order:stroke;stroke:var(--surface);stroke-width:3.5px;stroke-linejoin:round;font-weight:700}.rf__bracket-halo[data-astro-cid-fxsylqpx]{fill:none;stroke:var(--surface);stroke-width:4.5px;stroke-linejoin:round}.rf__small--ghost[data-astro-cid-fxsylqpx]{fill:#be185d;font-weight:700}.rf__small--start[data-astro-cid-fxsylqpx]{fill:var(--rf-start);font-weight:700}.rf__small--stop[data-astro-cid-fxsylqpx]{fill:var(--rf-stop);font-weight:700}.rf__end[data-astro-cid-fxsylqpx]{fill:var(--muted);font-size:13px;font-weight:700}.rf__end--rrna[data-astro-cid-fxsylqpx]{fill:var(--rf-rrna-text)}.rf__on-small[data-astro-cid-fxsylqpx]{fill:#713f12;letter-spacing:-.01em;font-size:12.5px;font-weight:700}.rf__on-small--name[data-astro-cid-fxsylqpx]{fill:#78350f;font-size:13.5px;font-weight:800}.rf__on-large[data-astro-cid-fxsylqpx]{fill:#0c4a6e;paint-order:stroke;stroke:#f0f9ffcc;stroke-width:3px;stroke-linejoin:round;font-size:13px;font-weight:800}.rf__letter[data-astro-cid-fxsylqpx]{font-family:var(--font-mono);pointer-events:none;font-size:13px;font-weight:800}.rf__site-letter[data-astro-cid-fxsylqpx]{fill:#1f2937;font-size:14px;font-weight:800}.rf__aa-letter[data-astro-cid-fxsylqpx]{fill:#0f172a;pointer-events:none;font-size:12px;font-weight:800}.rf__lsu[data-astro-cid-fxsylqpx]{stroke:#0284c7;stroke-width:1.4px}.rf__ssu[data-astro-cid-fxsylqpx]{stroke:#b45309;stroke-width:1.4px}.rf__large-ghost[data-astro-cid-fxsylqpx]{fill:#7dd3fc24;stroke:var(--rf-ghost);stroke-width:1.8px;stroke-dasharray:6 5}.rf__tunnel[data-astro-cid-fxsylqpx]{fill:none;stroke:#0c4a6e47;stroke-width:20px;stroke-linecap:round}.rf__tunnel-core[data-astro-cid-fxsylqpx]{fill:none;stroke:#0c4a6e38;stroke-width:12px;stroke-linecap:round}.rf__site[data-astro-cid-fxsylqpx]{stroke:#0f172a73;stroke-width:1.2px}.rf__trna-edge[data-astro-cid-fxsylqpx],.rf__cca-edge[data-astro-cid-fxsylqpx]{fill:none;stroke:#831843;stroke-width:3px}.rf__cca-edge[data-astro-cid-fxsylqpx]{stroke-width:6px;stroke-linecap:round}.rf__cca[data-astro-cid-fxsylqpx]{fill:none;stroke:#f9a8d4;stroke-width:3.5px;stroke-linecap:round}.rf__trna-hole[data-astro-cid-fxsylqpx]{fill:#fdf2f8;opacity:.75}.rf__trna--E[data-astro-cid-fxsylqpx]{opacity:.72}.rf__trna-ghost[data-astro-cid-fxsylqpx]{fill:#f472b614;stroke:#db2777;stroke-width:1.4px;stroke-dasharray:4 3;opacity:.6}.rf__tile[data-astro-cid-fxsylqpx]{stroke:#0f172a59;stroke-width:.8px}.rf__tile--dim[data-astro-cid-fxsylqpx]{opacity:.6}.rf__pair[data-astro-cid-fxsylqpx]{stroke:var(--rf-line);stroke-width:1.4px}.rf__codon-bar[data-astro-cid-fxsylqpx]{fill:none;stroke:var(--rf-line);stroke-width:1.6px;stroke-linecap:round}.rf__codon-bar--dim[data-astro-cid-fxsylqpx]{opacity:.4}.rf__rna[data-astro-cid-fxsylqpx],.rf__rna-edge[data-astro-cid-fxsylqpx],.rf__rrna[data-astro-cid-fxsylqpx],.rf__rrna-edge[data-astro-cid-fxsylqpx]{fill:none;stroke-linecap:round;stroke-linejoin:round}.rf__rna[data-astro-cid-fxsylqpx]{stroke:var(--rf-rna);stroke-width:4.5px}.rf__rna-edge[data-astro-cid-fxsylqpx]{stroke:var(--rf-rna-edge);stroke-width:6.5px}.rf__rrna[data-astro-cid-fxsylqpx]{stroke:var(--rf-rrna);stroke-width:4.5px}.rf__rrna-edge[data-astro-cid-fxsylqpx]{stroke:var(--rf-rrna-edge);stroke-width:6.5px}.rf__sd-glow[data-astro-cid-fxsylqpx]{fill:#fde04759;stroke:#ca8a04cc;stroke-width:1.3px}.rf__start-glow[data-astro-cid-fxsylqpx]{fill:#4ade804d;stroke:#16a34ad9;stroke-width:1.3px}.rf__chain[data-astro-cid-fxsylqpx]{fill:none;stroke:#94a3b8;stroke-width:2px;stroke-linejoin:round}.rf__chain--thin[data-astro-cid-fxsylqpx]{stroke-width:1.4px}.rf__aa[data-astro-cid-fxsylqpx]{stroke:#0f172a73;stroke-width:.8px}.rf__aa--small[data-astro-cid-fxsylqpx]{stroke-width:.5px}.rf__bond[data-astro-cid-fxsylqpx]{stroke:#f59e0b;stroke-width:2.2px;stroke-dasharray:2.5 2.5}.rf__leader[data-astro-cid-fxsylqpx]{fill:none;stroke:var(--muted);stroke-width:1.2px}.rf__leave[data-astro-cid-fxsylqpx]{fill:none;stroke:var(--muted);stroke-width:1.8px;stroke-linecap:round;stroke-dasharray:3 3}.rf__join[data-astro-cid-fxsylqpx]{fill:none;stroke:var(--rf-ghost);stroke-width:2.4px;stroke-linecap:round}.rf__move[data-astro-cid-fxsylqpx]{fill:none;stroke:#0ea5e9;stroke-width:3px;stroke-linecap:round}.rf__dim[data-astro-cid-fxsylqpx],.rf__bracket[data-astro-cid-fxsylqpx]{fill:none;stroke:var(--rf-line);stroke-width:1.4px}.rf__mark-start[data-astro-cid-fxsylqpx]{fill:#22c55e;stroke:#14532d;stroke-width:.8px}.rf__mark-stop[data-astro-cid-fxsylqpx]{fill:#ef4444;stroke:#7f1d1d;stroke-width:.8px}.rf__arrowhead[data-astro-cid-fxsylqpx]{fill:var(--rf-line)}.rf__arrowhead--move[data-astro-cid-fxsylqpx]{fill:#0ea5e9}.rf__arrowhead--sky[data-astro-cid-fxsylqpx]{fill:var(--rf-ghost)}@media (width<=420px){.rf__fig[data-astro-cid-fxsylqpx]{padding:.5rem .45rem .65rem}}.rnap{--rnap-cell:1.15rem;--rnap-row:1.35rem;--rnap-marks:1.15rem;--rnap-brackets:1.75rem}.rnap .rnap__stage{background:radial-gradient(80% 70% at 50% 38%,#21426d 0%,#102440 46%,#0a1424 100%);height:clamp(300px,46vw,420px)}@media (prefers-color-scheme:dark){.rnap .rnap__stage{background:radial-gradient(80% 70% at 50% 38%,#172c4d 0%,#0b1628 46%,#060a13 100%)}}.rnap .game__toast{max-width:82%;top:76%}.rnap__toast--info{background:#2563ebeb}.rnap__status strong{color:#fbbf24}.rnap__gripchip{font-variant-numeric:tabular-nums;white-space:nowrap;align-items:center;gap:.4rem;display:flex}.rnap__minibar{background:#94a3b859;border-radius:4px;width:4.2rem;height:7px;display:inline-block;overflow:hidden}.rnap__minibar span{background:#f87171;border-radius:4px;height:100%;transition:width .15s;display:block}.rnap__gripchip.is-weak .rnap__minibar span{background:#fbbf24}.rnap__gripchip.is-good .rnap__minibar span,.rnap__gripchip.is-strong .rnap__minibar span{background:#4ade80}.rnap__gripchip.is-good strong,.rnap__gripchip.is-strong strong{color:#4ade80}.rnap__speedchip{white-space:nowrap;font-variant-numeric:tabular-nums}.rnap__legend{flex-wrap:wrap;gap:.2rem .8rem;display:flex}.rnap__legend i,.rnap__rowname i{vertical-align:-.05em;border-radius:3px;width:.75em;height:.75em;margin-right:.15em;display:inline-block}.rnap .rnap__intro{overscroll-behavior:auto}.rnap__intro h4{margin-bottom:.6rem}.rnap__intro p{font-size:.95rem}.rnap__madeup{color:#cbd5e1;font-size:.82rem!important}.rnap__strip{background:var(--surface-2);border-radius:10px;gap:.4rem;margin-top:.7rem;padding:.4rem .5rem .45rem;display:flex}.rnap__labels{flex-direction:column;flex:none;display:flex}.rnap__labels>span{height:var(--rnap-row);align-items:center;display:flex}.rnap__labels>.rnap__rowname--marks:first-child{height:var(--rnap-marks)}.rnap__labels>.rnap__rowname--marks:last-child:not(:first-child){height:var(--rnap-brackets)}.rnap__rowname{color:var(--muted);white-space:nowrap;align-items:center;gap:.2rem;font-size:.75rem;font-weight:600;display:flex}.rnap__rowname small{font-size:.72rem;font-weight:400}.rnap__rowname em{background:var(--bg);color:var(--text);border-radius:4px;padding:0 .35em;font-size:.7rem;font-style:normal}.rnap__scroll{overscroll-behavior-x:contain;scrollbar-width:thin;border-radius:6px;flex:1;min-width:0;overflow:auto hidden}.rnap__scroll:focus-visible{outline:2px solid var(--accent);outline-offset:2px}.rnap__track{width:calc(var(--rnap-cell) * var(--count));position:relative}.rnap__marks,.rnap__brackets{height:var(--rnap-marks);position:relative}.rnap__brackets{height:var(--rnap-brackets)}.rnap__row{height:var(--rnap-row);align-items:center;display:flex}.rnap__cell{width:var(--rnap-cell);height:calc(var(--rnap-row) - 2px);font-family:var(--font-mono);color:#fff;text-shadow:0 1px 2px #00000073;border-right:1px solid #0000001a;flex:none;place-items:center;font-size:.78rem;font-weight:700;display:grid}.rnap__cell--empty{border-right-color:#0000}.rnap__cell--rna{border-radius:4px;animation:.25s ease-out rnap-pop}.rnap__cell--rna.is-hybrid{box-shadow:inset 0 0 0 2px #ffffffa6}@keyframes rnap-pop{0%{opacity:.2;transform:translateY(6px)scale(.7)}}.rnap__mark,.rnap__win,.rnap__bubble,.rnap__bracket{left:calc(var(--rnap-cell) * var(--i));width:calc(var(--rnap-cell) * var(--n));position:absolute}.rnap__mark{height:var(--rnap-marks);font-size:.72rem;font-weight:800;line-height:var(--rnap-marks);text-align:center;color:#fff;background:#dc2626;border-radius:5px 5px 0 0;transition:left .12s ease-out,background .15s;top:0}.rnap__mark.is-mid{background:#d97706}.rnap__mark.is-full{background:#16a34a}.rnap__mark--plus1{background:#c026d3;border-radius:5px}.rnap__win{top:calc(var(--rnap-marks) + var(--rnap-row) * var(--r));height:var(--rnap-row);pointer-events:none;border:2.5px solid #dc2626;border-radius:4px;transition:left .12s ease-out,border-color .15s;box-shadow:0 0 0 1.5px #ffffff8c}.rnap__win.is-mid{border-color:#d97706}.rnap__win.is-full{border-color:#16a34a}.rnap__bubble{top:calc(var(--rnap-marks) + var(--rnap-row) * var(--r) - 2px);height:calc(var(--rnap-row) * 2 + 4px);pointer-events:none;background:#c026d324;border:2px dashed #c026d3;border-radius:8px;transition:left .1s linear}.rnap__bracket{height:calc(var(--rnap-brackets) - .25rem);border:2px solid var(--muted);background:var(--surface);color:var(--text);border-top:0;border-radius:0 0 8px 8px;place-items:center;font-size:.85rem;font-weight:800;display:grid;top:.2rem}.rnap__bracket.is-right{border-color:var(--success);background:var(--success-soft)}.rnap__bracket.is-wrong{border-color:var(--danger);background:var(--danger-soft)}.rnap__bracket.is-passed:not(.is-right){opacity:.55}.rnap__panel{margin-top:.75rem}.rnap__readout{background:var(--surface-2);border-radius:10px;grid-template-columns:1fr 1fr;gap:.5rem .9rem;padding:.55rem .75rem .65rem;display:grid}.rnap__reading{color:var(--muted);grid-column:1/-1;margin:0;font-size:.85rem}.rnap__reading strong{color:var(--text)}.rnap__window{flex-direction:column;gap:.2rem;min-width:0;display:flex}.rnap__window-name{font-size:.82rem;font-weight:600}.rnap__window-name strong{font-variant-numeric:tabular-nums}.rnap__window.is-full .rnap__window-name strong{color:var(--success)}.rnap__window-letters{grid-template-columns:repeat(6,minmax(0,1fr));gap:3px;max-width:14rem;display:grid}.rnap__wl{--b:#64748b;border:2px dashed var(--border);height:1.95rem;font-family:var(--font-mono);color:var(--muted);border-radius:6px;place-items:center;font-size:1.05rem;font-weight:800;display:grid}.rnap__wl.is-match{border:2px solid var(--b);background:var(--b);color:#fff;text-shadow:0 1px 2px #0006}.rnap__window.is-full .rnap__window-letters{border-radius:8px;animation:.9s ease-out rnap-glow}@keyframes rnap-glow{0%{box-shadow:0 0 #16a34ab3}to{box-shadow:0 0 0 10px #16a34a00}}.rnap__window-want{color:var(--muted);font-size:.78rem}.rnap__grip{grid-column:1/-1;align-items:center;gap:.7rem;display:flex}.rnap__grip-label{white-space:nowrap;font-variant-numeric:tabular-nums;font-size:.9rem}.rnap__grip-label strong{font-size:1.15rem}.rnap__grip-bar{background:var(--border);border-radius:6px;flex:1;height:12px;position:relative}.rnap__grip-bar span{background:#dc2626;border-radius:6px;transition:width .15s ease-out,background .15s;position:absolute;inset:0 auto 0 0}.rnap__grip.is-weak .rnap__grip-bar span{background:#d97706}.rnap__grip.is-good .rnap__grip-bar span,.rnap__grip.is-strong .rnap__grip-bar span{background:#16a34a}.rnap__grip.is-strong .rnap__grip-bar span{box-shadow:0 0 10px #16a34ab3}.rnap__grip-bar i{background:var(--text);border-radius:2px;width:3px;position:absolute;top:-4px;bottom:-4px;transform:translate(-50%)}.rnap__controls{flex-direction:column;gap:.5rem;margin-top:.6rem;display:flex}.rnap__slider input{width:100%;min-height:2.3rem;accent-color:var(--accent)}.rnap__buttons{grid-template-columns:repeat(4,minmax(0,1fr));gap:.45rem;display:grid}.rnap__buttons--main{grid-template-columns:1fr 1.4fr}.rnap__move,.rnap__turn,.rnap__bind{justify-content:center;min-height:2.9rem;font-size:1rem}.rnap__bind{font-size:1.05rem}.rnap__question p{margin:0 0 .55rem}.rnap__choices{grid-template-columns:repeat(auto-fit,minmax(10rem,1fr));gap:.5rem;display:grid}.rnap__choice{text-align:center;white-space:normal;justify-content:center;min-height:3rem;line-height:1.25}.rnap__choice.is-right{border-color:var(--success);background:var(--success-soft)}.rnap__choice.is-wrong{border-color:var(--danger);background:var(--danger-soft)}.rnap__strandpick{flex-direction:column;gap:.35rem;min-height:3.8rem}.rnap__arrowline{font-family:var(--font-mono);color:var(--muted);font-weight:600}.rnap__answer{border-radius:8px;margin:.6rem 0 0;padding:.45rem .7rem}.rnap__answer.is-good{background:var(--success-soft)}.rnap__answer.is-bad{background:var(--danger-soft)}.rnap__predict{margin:0 0 .5rem;font-size:.95rem}.rnap__cards{grid-template-columns:repeat(auto-fit,minmax(13.5rem,1fr));gap:.5rem;display:grid}.rnap__card{border:2px solid var(--border);background:var(--surface);min-height:3.3rem;color:var(--text);font:inherit;text-align:left;cursor:pointer;touch-action:manipulation;border-radius:10px;align-items:center;gap:.6rem;padding:.5rem .65rem;display:flex}.rnap__card:hover:not(:disabled){border-color:var(--accent)}.rnap__card:disabled{cursor:default}.rnap__card:focus-visible{outline:2px solid var(--accent);outline-offset:2px}.rnap__card-id{background:var(--surface-2);border-radius:50%;flex:none;place-items:center;width:2.1rem;height:2.1rem;font-size:1.05rem;font-weight:800;display:grid}.rnap__card-body{flex-direction:column;gap:.1rem;min-width:0;display:flex}.rnap__card-where{color:var(--muted);font-size:.75rem}.rnap__card .rnap__seq{word-break:break-all;font-size:.84rem;line-height:1.5}.rnap__card.is-right{border-color:var(--success);background:var(--success-soft)}.rnap__card.is-wrong{border-color:var(--danger);background:var(--danger-soft)}.rnap__card.is-passed{opacity:.6}.rnap__card.is-right .rnap__card-id{background:var(--success);color:var(--surface)}.rnap__seq{font-family:var(--font-mono);letter-spacing:.02em;font-weight:700}.rnap__seq--wrap{word-break:break-all}.rnap__l--A{color:#15803d}.rnap__l--T{color:#dc2626}.rnap__l--G{color:#a16207}.rnap__l--C{color:#1d4ed8}.rnap__l--U{color:#9333ea}.rnap__arm{background:#eab30833;border-radius:3px;box-shadow:inset 0 -2px #eab308cc}.rnap__arm--back{background:#3b82f629;box-shadow:inset 0 -2px #3b82f6bf}.rnap__trun{box-shadow:inset 0 -2px #dc2626bf}.rnap__speed{flex-direction:column;gap:.3rem;margin-top:.75rem;display:flex}.rnap__speed-label{font-size:.95rem}.rnap__speed-label strong{color:var(--accent);font-variant-numeric:tabular-nums;font-size:1.1rem}.rnap__speed input{width:100%;min-height:2.3rem;accent-color:var(--accent)}.rnap__presets{flex-wrap:wrap;gap:.4rem;display:flex}.rnap__preset.is-on{border-color:var(--accent);background:var(--accent-soft)}.rnap__ok{color:var(--success);font-weight:600}.rnap__go{margin-top:.75rem;display:flex}.rnap__go .rnap__bind{flex:1}.rnap__tally{color:var(--muted);margin:.1rem 0 .5rem;font-size:.88rem}.rnap__done p{margin:0 0 .6rem}.rnap__readout-rna{font-size:.9rem}.rnap__after{margin-top:.4rem}.rnap__note{margin:.8rem 0 0;font-size:.8rem}@media (pointer:coarse){.rnap .game__level,.rnap .game__sound{min-height:2.75rem}}@media (prefers-color-scheme:dark){.rnap__l--A{color:#4ade80}.rnap__l--T{color:#f87171}.rnap__l--G{color:#facc15}.rnap__l--C{color:#60a5fa}.rnap__l--U{color:#c084fc}}@media (prefers-reduced-motion:reduce){.rnap__cell--rna,.rnap__window.is-full .rnap__window-letters{animation:none}.rnap__mark,.rnap__win,.rnap__bubble,.rnap__grip-bar span{transition:none}}@media (width<=640px){.rnap{--rnap-cell:1.08rem;--rnap-row:1.3rem}.rnap .rnap__stage{height:clamp(270px,76vw,320px)}.rnap .rnap__stage.is-intro{height:clamp(380px,112vw,460px)}.rnap__intro p{margin-bottom:.65rem;font-size:.9rem}.rnap__buttons--main{grid-template-columns:1fr 1fr}.rnap__rowname small,.rnap__rowname em,.rnap__hide-sm{display:none}.rnap .game__toast{white-space:nowrap;padding:.45rem .75rem;font-size:.9rem;top:84%}.rnap__readout{gap:.4rem .6rem;padding:.5rem .55rem .6rem}.rnap__wl{height:1.75rem;font-size:.95rem}.rnap__cards{grid-template-columns:1fr}.rnap__card{min-height:3rem;padding:.4rem .55rem}.rnap__legend{gap:.1rem .6rem}}.orf{--lw:16px;--ruler-h:18px;--dna-h:40px;--lane-h:50px;--tile-h:44px;--label-w:2.6rem;--map-h:66px;--orf-stage-a:#f8fafc;--orf-stage-b:#eef2f7;--orf-strip:#fff;--orf-line:#dbe2ea;--orf-lane-sel:#0f766e12;--orf-bracket:#94a3b8;--orf-bracket-odd:#94a3b824;--orf-map-bg:#e5eaf1;--orf-map-lane:#f1f5f9;--orf-map-sel:#dff3f0;--aa-oily:#fdecc8;--aa-oily-t:#92400e;--aa-polar:#d5f5e3;--aa-polar-t:#065f46;--aa-plus:#dbe7fe;--aa-plus-t:#1e40af;--aa-minus:#f9e1fb;--aa-minus-t:#86198f;--aa-atg:#c9f7d6;--aa-atg-t:#14532d;--aa-atg-b:#16a34a;--aa-tga:#efe3ff;--aa-tga-t:#6b21a8;--stop-a:#ef4444;--stop-b:#b91c1c;--base-A:#15803d;--base-T:#dc2626;--base-G:#a16207;--base-C:#1d4ed8}@media (prefers-color-scheme:dark){.orf{--orf-stage-a:#0f1a22;--orf-stage-b:#0b141b;--orf-strip:#111c24;--orf-line:#24323b;--orf-lane-sel:#2dd4bf14;--orf-bracket:#5b6b7a;--orf-bracket-odd:#94a3b814;--orf-map-bg:#18242c;--orf-map-lane:#1d2b34;--orf-map-sel:#163a38;--aa-oily:#3d2c0c;--aa-oily-t:#fcd34d;--aa-polar:#0c3324;--aa-polar-t:#6ee7b7;--aa-plus:#14254a;--aa-plus-t:#93c5fd;--aa-minus:#3a1040;--aa-minus-t:#f0abfc;--aa-atg:#0f3d22;--aa-atg-t:#86efac;--aa-atg-b:#22c55e;--aa-tga:#2c1648;--aa-tga-t:#d8b4fe;--stop-a:#ef4444;--stop-b:#991b1b;--base-A:#4ade80;--base-T:#f87171;--base-G:#facc15;--base-C:#60a5fa}}.orf__stage{border:1px solid var(--border);background:linear-gradient(180deg, var(--orf-stage-a), var(--orf-stage-b));border-radius:12px;min-height:21rem;padding:.55rem .6rem .65rem;position:relative;overflow:hidden}.orf .game__toast{z-index:5;top:34%}.orf__toast{box-shadow:0 8px 24px #00000040}.orf__intro{z-index:6;border-radius:12px}.orf__intro p{font-size:.95rem}.orf__intro .button{margin-top:.2rem}.orf__hud{flex-wrap:wrap;gap:.3rem;font-size:.74rem;display:flex}.orf__chip{border:1px solid var(--border);background:var(--surface);color:var(--muted);white-space:nowrap;border-radius:999px;align-items:center;gap:.25em;padding:.15em .6em;display:inline-flex}.orf__chip b{font-family:var(--font-mono);color:#fff;background:var(--stop-a);border-radius:4px;padding:0 .25em;font-size:.95em;font-weight:700}.orf__chip--code.is-standard{color:var(--text);border-color:#f59e0b}.orf__chip--strand{color:var(--text);border-color:var(--accent)}.orf__chip--strand.is-rev{background:color-mix(in srgb, #a855f7 12%, var(--surface));border-color:#a855f7}.orf__chip--src{margin-left:auto}.orf__task{min-height:2.8em;margin:.4rem 0 .45rem;font-size:.93rem;line-height:1.4}.orf__map{grid-template-columns:var(--label-w) minmax(0, 1fr);grid-template-rows:auto auto;display:grid}.orf__map-labels{height:var(--map-h);flex-direction:column;display:flex}.orf__map-label{font:inherit;color:var(--muted);font-variant-numeric:tabular-nums;cursor:pointer;background:0 0;border:0;flex:1;place-items:center;padding:0;font-size:.7rem;font-weight:700;display:grid}.orf__map-label.is-selected{color:var(--accent)}.orf__map-body{height:var(--map-h);background:var(--orf-map-bg);cursor:pointer;touch-action:pan-y;-webkit-user-select:none;user-select:none;-webkit-tap-highlight-color:transparent;border-radius:7px;position:relative;overflow:hidden}.orf__map-svg{width:100%;height:100%;display:block}.orf__map-bg{fill:var(--orf-map-lane)}.orf__map-lane.is-selected .orf__map-bg{fill:var(--orf-map-sel)}.orf__m--oily{fill:#f6c56b}.orf__m--polar{fill:#7fd8ac}.orf__m--plus{fill:#8db4f8}.orf__m--minus{fill:#e59af0}.orf__m--atg,.orf__m--atg-tick{fill:#16a34a}.orf__m--stop{fill:#dc2626}@media (prefers-color-scheme:dark){.orf__m--oily{fill:#a87a23}.orf__m--polar{fill:#2c8a63}.orf__m--plus{fill:#3b62b0}.orf__m--minus{fill:#9c4aa8}.orf__m--atg,.orf__m--atg-tick{fill:#22c55e}.orf__m--stop{fill:#f87171}}.orf__map-svg.is-hidden .orf__m{opacity:0}.orf__map-svg.is-scanning .orf__m{animation:orf-fade-in .22s ease-out calc(var(--ld,0s) + var(--t,0) * var(--dur,1s)) both}.orf__map-band{fill:none;stroke-width:2px}.orf__map-band--found{fill:#22c55e47;stroke:#16a34a;stroke-width:2.5px;animation:1.8s ease-in-out infinite orf-glow}.orf__map-band--pick{fill:#facc154d;stroke:#ca8a04}.orf__map-band--longest{fill:#f59e0b38;stroke:#d97706;stroke-dasharray:4 3}.orf__map-pin--start{fill:#16a34a}.orf__map-pin--stop{fill:#dc2626}.orf__map-view{fill:#0f766e12;stroke:var(--accent);stroke-width:2px;pointer-events:none}.orf__map-sweep{pointer-events:none;width:4px;animation:orf-sweep var(--dur) linear var(--ld) both;background:#38bdf8;border-radius:2px;margin-left:-2px;position:absolute;left:0;box-shadow:0 0 10px 3px #38bdf8bf,-18px 0 22px #38bdf840}.orf__map-ends{color:var(--muted);font-variant-numeric:tabular-nums;grid-column:2;justify-content:space-between;padding:.1rem .15rem 0;font-size:.68rem;display:flex}.orf__strip{grid-template-columns:var(--label-w) minmax(0, 1fr);margin-top:.45rem;display:grid}.orf__labels{flex-direction:column;display:flex}.orf__label{color:var(--muted);text-align:center;place-items:center;font-size:.72rem;font-weight:700;line-height:1.1;display:grid}.orf__label--ruler{height:var(--ruler-h);font-size:.62rem;font-weight:500}.orf__label--dna{height:var(--dna-h);color:var(--text)}.orf__label--dna em{color:var(--muted);font-size:.66rem;font-style:normal;display:block}.orf__lane-name{height:var(--lane-h);width:100%;font:inherit;font-variant-numeric:tabular-nums;color:var(--muted);cursor:pointer;touch-action:manipulation;background:0 0;border:0;border-top:1px solid #0000;border-radius:8px 0 0 8px;margin:0;padding:0;font-size:.9rem;font-weight:800}.orf__lane-name.is-selected{color:var(--accent);background:var(--orf-lane-sel);box-shadow:inset 3px 0 0 var(--accent)}.orf__lane-name:focus-visible{outline:2px solid var(--accent);outline-offset:-2px}.orf__viewport{overscroll-behavior-x:contain;scrollbar-width:thin;background:var(--orf-strip);border:1px solid var(--orf-line);border-radius:8px;position:relative;overflow:auto hidden}.orf__viewport:focus-visible{outline:2px solid var(--accent);outline-offset:2px}.orf__track{margin-right:1.6rem;position:relative}.orf__ruler{height:var(--ruler-h);position:relative}.orf__tick{border-left:1px solid var(--orf-bracket);height:calc(var(--ruler-h) - 3px);color:var(--muted);font-variant-numeric:tabular-nums;white-space:nowrap;padding-left:2px;font-size:.6rem;line-height:1;position:absolute;top:3px}.orf__dnarow{height:var(--dna-h);position:relative}.orf__brackets{transition:transform .5s cubic-bezier(.34,1.56,.64,1);position:absolute;inset:0}.orf__bracket{width:calc(var(--lw) * 3);border:2px solid var(--orf-bracket);border-top-width:0;border-radius:0 0 8px 8px;transition:border-color .3s,background-color .3s,opacity .3s;position:absolute;top:4px;bottom:4px}.orf__bracket.is-odd{background:var(--orf-bracket-odd)}.orf__bracket.is-stop{border-color:var(--stop-a);background:color-mix(in srgb, var(--stop-a) 16%, transparent);border-width:0 3px 3px}.orf__bracket.is-atg{border-color:var(--aa-atg-b);background:color-mix(in srgb, var(--aa-atg-b) 16%, transparent);border-width:0 3px 3px}.orf__bracket.is-off{opacity:0}.orf__dna{align-items:center;display:flex;position:absolute;inset:0 0 6px}.orf__b{width:var(--lw);text-align:center;font-family:var(--font-mono);flex:none;font-size:.98rem;font-weight:800;line-height:1}.orf__b--A{color:var(--base-A)}.orf__b--T{color:var(--base-T)}.orf__b--G{color:var(--base-G)}.orf__b--C{color:var(--base-C)}.orf__end{color:var(--muted);margin-left:.25rem;font-size:.72rem;font-weight:700;position:absolute;top:50%;transform:translateY(-60%)}.orf__pin{z-index:3;top:calc(-1 * var(--ruler-h) + 1px);width:calc(var(--lw) * 3);height:calc(var(--ruler-h) - 2px);letter-spacing:.06em;color:#fff;border-radius:5px 5px 0 0;place-items:center;font-size:.56rem;font-weight:800;animation:.45s cubic-bezier(.34,1.56,.64,1) orf-drop;display:grid;position:absolute}.orf__pin--start{background:#16a34a}.orf__pin--stop{background:#dc2626}.orf__lanes{position:relative}.orf__lane{height:var(--lane-h);border-top:1px dashed var(--orf-line);cursor:pointer;-webkit-tap-highlight-color:transparent;position:relative;overflow:hidden}.orf__lane.is-selected{background:var(--orf-lane-sel)}.orf__tile{z-index:1;top:calc((var(--lane-h) - var(--tile-h)) / 2);height:var(--tile-h);width:calc(var(--lw) * 3 - 3px);pointer-events:none;border-radius:9px;flex-direction:column;justify-content:center;align-items:center;gap:2px;margin-left:1.5px;line-height:1;display:flex;position:absolute;box-shadow:inset 0 -2px #00000014}.orf__tile b{font-size:1.08rem;font-weight:800}.orf__tile small{opacity:.75;font-size:.58rem;font-weight:600}.orf__tile--oily{background:var(--aa-oily);color:var(--aa-oily-t)}.orf__tile--polar{background:var(--aa-polar);color:var(--aa-polar-t)}.orf__tile--plus{background:var(--aa-plus);color:var(--aa-plus-t)}.orf__tile--minus{background:var(--aa-minus);color:var(--aa-minus-t)}.orf__tile.is-atg{background:var(--aa-atg);color:var(--aa-atg-t);box-shadow:inset 0 0 0 2px var(--aa-atg-b)}.orf__tile.is-atg:before{content:"";border:5px solid #0000;border-left:7px solid var(--aa-atg-b);border-right-width:0;position:absolute;top:3px;left:4px}.orf__tile.is-tga{background:var(--aa-tga);color:var(--aa-tga-t);box-shadow:inset 0 0 0 2px #a855f7}.orf__tile--stop{z-index:2;height:calc(var(--lane-h) - 3px);background:linear-gradient(180deg, var(--stop-a), var(--stop-b));color:#fff;top:1px;box-shadow:inset 0 0 0 2px #7f1d1d99,0 2px 8px #dc262666}.orf__tile--stop b{letter-spacing:.08em;font-size:.66rem}.orf__tile--stop small{font-family:var(--font-mono);opacity:.95;font-size:.66rem}.orf__lanes.is-hidden .orf__tile{opacity:0}.orf__lanes.is-scanning .orf__tile{animation:orf-tile-in .3s cubic-bezier(.34, 1.56, .64, 1) calc(var(--ld,0s) + var(--t,0) * var(--dur,1s)) both}.orf__lanes.is-scanning .orf__tile--stop{animation-name:orf-stop-in;animation-duration:.45s}.orf__lanes.is-scanning .orf__lane:after{content:"";z-index:3;pointer-events:none;animation:orf-wipe var(--dur,1s) linear var(--ld,0s) both;background:linear-gradient(90deg,#0000 calc(100% - 70px),#38bdf84d calc(100% - 4px),#38bdf8 calc(100% - 3px) 100%);position:absolute;inset:0}.orf__lane.is-flash-0 .orf__tile--stop{animation:.5s ease-in-out 3 orf-flash-a}.orf__lane.is-flash-1 .orf__tile--stop{animation:.5s ease-in-out 3 orf-flash-b}.orf__lanes.is-morphing .orf__tile.is-tga{animation:.9s ease-out both orf-morph}.orf__band{z-index:0;pointer-events:none;border-radius:11px;position:absolute;top:1px;bottom:1px}.orf__band--found,.orf__band--pick,.orf__band--longest{z-index:3}.orf__band-fill{animation:orf-fill var(--fill,0s) linear both;background:#22c55e24;border-radius:11px;position:absolute;inset:0;box-shadow:inset 0 0 0 3px #16a34a,inset 0 0 14px #22c55e8c}.orf__band--pick{background:#facc151f;animation:.25s ease-out orf-fade-in;box-shadow:inset 0 0 0 3px #ca8a04,inset 0 0 12px #facc1580}.orf__band--longest{box-sizing:border-box;background:#f59e0b14;border:3px dashed #d97706}.orf__ribosome{z-index:4;width:30px;height:30px;animation:orf-ride var(--fill,0s) linear both;background:radial-gradient(circle at 35% 30%,#e0f2fe,#38bdf8 45%,#0369a1);border-radius:50% 50% 45% 45%;margin:-15px 0 0 -15px;position:absolute;top:50%;left:0;box-shadow:0 0 14px #38bdf8cc}.orf__tapfx{z-index:4;top:calc((var(--lane-h) - var(--tile-h)) / 2);height:var(--tile-h);width:calc(var(--lw) * 3);pointer-events:none;border-radius:10px;animation:.7s ease-out forwards orf-ripple;position:absolute}.orf__tapfx.is-good{box-shadow:0 0 0 3px #22c55e}.orf__tapfx.is-bad{animation-name:orf-shake;box-shadow:0 0 0 3px #ef4444}.orf__stage.is-flip-out .orf__viewport,.orf__stage.is-flip-out .orf__map-body{transition:transform .2s ease-in;transform:perspective(600px)rotateX(90deg)}.orf__stage.is-flip-in .orf__viewport,.orf__stage.is-flip-in .orf__map-body{animation:.26s ease-out orf-flip-in}.orf__stage.is-rev .orf__viewport{border-color:#c4a2f5}.orf__dna.is-shuffling .orf__b{animation:.55s cubic-bezier(.34,1.56,.64,1) both orf-tumble-a}.orf__dna.is-shuffling .orf__b:nth-child(3n){animation-name:orf-tumble-b;animation-delay:50ms}.orf__dna.is-shuffling .orf__b:nth-child(3n+1){animation-name:orf-tumble-c;animation-delay:.1s}.orf__controls{margin-top:.7rem}.orf__controls:empty{display:none}.orf__answers{grid-template-columns:repeat(3,minmax(0,1fr));gap:.5rem;display:grid}.orf__answer{border:2px solid var(--border);background:var(--surface);min-height:3.5rem;color:var(--text);font:inherit;cursor:pointer;border-radius:12px;flex-direction:column;justify-content:center;align-items:center;gap:.15rem;padding:.4rem .3rem;transition:transform 80ms,border-color .2s,background .2s;display:flex}.orf__answer:hover:not(:disabled){border-color:var(--accent)}.orf__answer:active:not(:disabled){transform:scale(.96)}.orf__answer:disabled{cursor:default}.orf__answer-frame{font-size:1.05rem;font-weight:800}.orf__answer-sub{color:var(--muted);font-size:.75rem}.orf__answer.is-wrong{border-color:var(--danger);background:var(--danger-soft)}.orf__answer.is-wrong .orf__answer-frame{text-decoration:line-through;text-decoration-color:var(--danger)}.orf__answer.is-right{border-color:var(--success);background:var(--success-soft)}.orf__codes{grid-template-columns:repeat(2,minmax(0,1fr));gap:.5rem;display:grid}.orf__code{border:2px solid var(--border);background:var(--surface);min-height:3.4rem;color:var(--text);font:inherit;cursor:pointer;border-radius:12px;flex-direction:column;justify-content:center;align-items:center;gap:.15rem;padding:.4rem;display:flex}.orf__code span{color:var(--muted);font-size:.75rem}.orf__code.is-on{border-color:var(--accent);background:var(--accent-soft)}.orf__code:disabled{cursor:default;opacity:.6}.orf__code.is-on:disabled{opacity:1}.orf__pulse{animation:1.5s ease-in-out infinite orf-pulse}.orf__flip svg{flex:none}.orf__msg{margin-top:.6rem}.orf__inspect{background:color-mix(in srgb, #eab308 12%, var(--surface));border-left:4px solid #ca8a04;border-radius:9px;margin:.6rem 0 0;padding:.55rem .8rem;font-size:.93rem}.orf__inspect p{margin:0}.orf__chart{margin:.8rem 0 0}.orf__chart figcaption{color:var(--muted);margin-bottom:.3rem;font-size:.8rem;font-weight:600}.orf__bars{border-bottom:2px solid var(--border);grid-template-columns:repeat(6,minmax(0,1fr));align-items:end;gap:.4rem;height:120px;padding:0 .2rem;display:grid}.orf__bar{flex-direction:column;justify-content:flex-end;align-items:center;height:100%;display:flex;position:relative}.orf__bar-fill{background:linear-gradient(#fbbf24,#d97706);border-radius:6px 6px 0 0;width:70%;transition:height .6s cubic-bezier(.34,1.56,.64,1)}.orf__bar.is-gene .orf__bar-fill{background:linear-gradient(#4ade80,#15803d)}.orf__bar.is-empty .orf__bar-fill{background:var(--border)}.orf__bar-v{font-variant-numeric:tabular-nums;font-size:.75rem;font-weight:700}.orf__bar-label{color:var(--muted);font-size:.72rem;position:absolute;bottom:-1.3rem}.orf__chart{padding-bottom:1.3rem}.orf__question{border:2px solid var(--accent);background:var(--accent-soft);border-radius:10px;margin-top:.9rem;padding:.7rem .9rem}.orf__question p{margin:0 0 .5rem}.orf__options{grid-template-columns:repeat(4,minmax(0,1fr));gap:.45rem;display:grid}.orf__option{justify-content:center;min-height:2.75rem}.orf__option.is-wrong{border-color:var(--danger);background:var(--danger-soft)}.orf__legend{color:var(--muted);flex-wrap:wrap;gap:.25rem .85rem;margin:.7rem 0 0;font-size:.78rem;display:flex}.orf__legend span{align-items:center;gap:.3em;display:inline-flex}.orf__key{border-radius:3px;width:.95em;height:.95em;display:inline-block}.orf__key--oily{background:var(--aa-oily);box-shadow:inset 0 0 0 1px var(--aa-oily-t)}.orf__key--polar{background:var(--aa-polar);box-shadow:inset 0 0 0 1px var(--aa-polar-t)}.orf__key--plus{background:var(--aa-plus);box-shadow:inset 0 0 0 1px var(--aa-plus-t)}.orf__key--minus{background:var(--aa-minus);box-shadow:inset 0 0 0 1px var(--aa-minus-t)}.orf__key--atg{background:var(--aa-atg);box-shadow:inset 0 0 0 2px var(--aa-atg-b)}.orf__key--stop{background:linear-gradient(180deg, var(--stop-a), var(--stop-b))}.orf__done-sub{color:var(--muted);margin:-.2rem 0 .4rem;font-size:.85rem}.orf__done p{margin:0 0 .6rem}.orf__after{margin-top:.7rem}.orf__chain{flex-wrap:wrap;gap:3px;margin:.2rem 0 .7rem;display:flex}.orf__bead{width:22px;height:22px;animation:orf-bead .35s cubic-bezier(.34, 1.56, .64, 1) calc(var(--i) * 22ms) both;border-radius:50%;place-items:center;font-size:11px;font-weight:800;line-height:1;display:inline-grid}.orf__bead--oily{color:#7c2d12;background:radial-gradient(circle at 35% 30%,#fff7d6,#fcd34d 40%,#d97706)}.orf__bead--polar{color:#064e3b;background:radial-gradient(circle at 35% 30%,#ecfdf5,#6ee7b7 40%,#059669)}.orf__bead--plus{color:#1e3a8a;background:radial-gradient(circle at 35% 30%,#eff6ff,#93c5fd 40%,#2563eb)}.orf__bead--minus{color:#701a75;background:radial-gradient(circle at 35% 30%,#fdf4ff,#f0abfc 40%,#c026d3)}.orf__chain-more{color:var(--muted);align-self:center;margin-left:.3rem;font-size:.78rem}.orf__genbank{border:1px solid var(--border);background:var(--surface);border-radius:10px;margin:.8rem 0 .3rem;padding:.7rem .9rem .5rem;animation:.5s ease-out orf-drop}.orf__genbank-title{font-weight:700;margin:0 0 .45rem!important}.orf__genbank dl{grid-template-columns:auto minmax(0,1fr);gap:.2rem .9rem;margin:0 0 .5rem;font-size:.92rem;display:grid}.orf__genbank dt{color:var(--muted);font-weight:600}.orf__genbank dd{overflow-wrap:anywhere;margin:0}.orf__genbank-note{font-size:.88rem}.orf__table{margin:.2rem 0 .8rem;font-size:.84rem}.orf__table td:nth-child(n+2),.orf__table th:nth-child(n+2){text-align:right;white-space:nowrap;font-variant-numeric:tabular-nums}@keyframes orf-fade-in{0%{opacity:0}}@keyframes orf-tile-in{0%{opacity:0;transform:translateY(10px)scale(.6)}}@keyframes orf-stop-in{0%{opacity:0;transform:scaleY(.2)}55%{opacity:1;filter:brightness(1.6);transform:scaleY(1.12)}to{transform:scaleY(1)}}@keyframes orf-wipe{0%{opacity:1;transform:translate(-100%)}94%{opacity:1}to{opacity:0;transform:translate(0)}}@keyframes orf-sweep{0%{opacity:0;left:0}4%{opacity:1}96%{opacity:1}to{opacity:0;left:100%}}@keyframes orf-flash-a{50%{filter:brightness(1.5);transform:scale(1.18);box-shadow:0 0 16px 4px #ef4444cc}}@keyframes orf-flash-b{50%{filter:brightness(1.5);transform:scale(1.18);box-shadow:0 0 16px 4px #ef4444cc}}@keyframes orf-morph{0%{background:var(--stop-a);color:#fff;transform:rotateY(90deg)scale(1.1)}45%{transform:rotateY(0)scale(1.2);box-shadow:inset 0 0 0 2px #a855f7,0 0 18px 4px #a855f7b3}to{transform:none}}@keyframes orf-fill{0%{clip-path:inset(0 100% 0 0 round 11px)}to{clip-path:inset(0 round 11px)}}@keyframes orf-ride{0%{opacity:1;left:0}92%{opacity:1}to{opacity:0;left:100%}}@keyframes orf-ripple{0%{opacity:1;transform:scale(.9)}to{opacity:0;transform:scale(1.25)}}@keyframes orf-shake{0%,to{opacity:1;transform:translate(0)}20%{transform:translate(-5px)}40%{transform:translate(5px)}60%{transform:translate(-3px)}80%{opacity:.8;transform:translate(3px)}to{opacity:0}}@keyframes orf-drop{0%{opacity:0;transform:translateY(-8px)}}@keyframes orf-flip-in{0%{transform:perspective(600px)rotateX(-90deg)}}@keyframes orf-tumble-a{0%{opacity:0;transform:translateY(-18px)rotate(-90deg)}}@keyframes orf-tumble-b{0%{opacity:0;transform:translateY(18px)rotate(120deg)}}@keyframes orf-tumble-c{0%{opacity:0;transform:translate(-12px)scale(.3)}}@keyframes orf-pulse{0%,to{box-shadow:0 0 #0f766e73}50%{box-shadow:0 0 0 6px #0f766e00}}@keyframes orf-glow{50%{fill:#22c55e73}}@keyframes orf-bead{0%{opacity:0;transform:scale(.2)}}@media (prefers-reduced-motion:reduce){.orf__brackets{transition:none}.orf__lanes.is-scanning .orf__tile,.orf__lanes.is-scanning .orf__lane:after,.orf__map-svg.is-scanning .orf__m,.orf__map-sweep,.orf__dna.is-shuffling .orf__b,.orf__lanes.is-morphing .orf__tile.is-tga,.orf__lane.is-flash-0 .orf__tile--stop,.orf__lane.is-flash-1 .orf__tile--stop,.orf__band-fill,.orf__map-band--found,.orf__ribosome,.orf__bead,.orf__pulse{animation:none}.orf__ribosome{display:none}}@media (width<=640px){.orf{--lw:15px;--label-w:2.3rem;--map-h:60px;--dna-h:38px}.orf__stage{padding:.45rem .45rem .55rem}.orf__chip--src{margin-left:0}.orf__task{font-size:.88rem}.orf__options{grid-template-columns:repeat(2,minmax(0,1fr))}.orf__answer-sub{font-size:.7rem}.orf__genbank dl{grid-template-columns:minmax(0,1fr);gap:0}.orf__genbank dd{margin-bottom:.35rem}}@media (pointer:coarse){.orf .game__level,.orf .game__sound{min-height:2.75rem}}.rush{--rush-pink:#db2777;--rush-rf:#7e22ce;--rush-ok:#16a34a;--rush-bad:#dc2626}@media (prefers-color-scheme:dark){.rush{--rush-pink:#f472b6;--rush-rf:#c084fc;--rush-ok:#4ade80;--rush-bad:#f87171}}.rush .rush__stage{background:radial-gradient(120% 95% at 45% 35%,#21436b 0%,#112644 52%,#0a1629 100%);height:clamp(340px,46vw,440px)}@media (prefers-color-scheme:dark){.rush .rush__stage{background:radial-gradient(120% 95% at 45% 35%,#182f4f 0%,#0c1a33 55%,#060c19 100%)}}.rush .game__toast{top:15%}.rush__intro h4{margin-bottom:.6rem}.rush__intro p{font-size:.95rem}.rush__diagram{background:#0f172a99;border-radius:10px;grid-template-columns:auto auto auto auto;align-items:center;gap:.35rem .45rem;width:max-content;max-width:100%;margin:0 auto .9rem;padding:.5rem .8rem;display:grid}.rush__diagram-name{text-align:right;color:#cbd5e1;font-size:.82rem;font-weight:600}.rush__intro .rush__end{color:#fbbf24}.rush__letters{gap:3px;display:inline-flex}.rush__tile{width:1.9rem;height:1.95rem;font-family:var(--font-mono);color:#fff;background:var(--base);text-shadow:0 1px 2px #00000080;border-radius:6px;place-items:center;font-size:1.1rem;font-weight:800;line-height:1;display:inline-grid}.rush__tile.is-dim{border:1.5px dashed var(--border);color:var(--muted);text-shadow:none;background:0 0}.rush__tile.is-ok{box-shadow:0 0 0 2.5px var(--rush-ok)}.rush__tile.is-bad{box-shadow:0 0 0 2.5px var(--rush-bad);opacity:.75;text-decoration:line-through 2px}.rush__end{color:var(--muted);text-align:center;min-width:1.1em;font-size:.75rem;font-weight:700}.rush__line{align-items:center;gap:.25rem;display:inline-flex}.rush__codon{letter-spacing:.04em;font-weight:700}.rush__decoder{background:var(--surface-2);border-radius:10px;grid-template-columns:minmax(0,1fr) auto minmax(0,1fr);align-items:center;gap:.6rem;margin-top:.6rem;padding:.45rem .7rem;display:grid}.rush__decoder.is-idle{opacity:.6}.rush__count{font-variant-numeric:tabular-nums;flex-direction:column;gap:.1rem;font-size:.85rem;line-height:1.3;display:flex}.rush__count strong{color:var(--accent);font-size:1.05rem}.rush__miss{color:var(--danger)}.rush__time strong{font-size:1.3rem}.rush__time.is-late strong{color:var(--danger)}.rush__pair{flex-direction:column;align-items:center;gap:3px;display:flex}.rush__site{letter-spacing:.07em;text-transform:uppercase;color:#15803d;font-size:.7rem;font-weight:700}@media (prefers-color-scheme:dark){.rush__site{color:#4ade80}}.rush__box{justify-self:end;font-size:.78rem;line-height:1.32}.rush__box-line{border-radius:4px;align-items:baseline;gap:.4rem;padding:0 .3rem;display:flex}.rush__box-line code{background:0 0;border:0;padding:0;font-size:1em}.rush__box-line.is-here{background:var(--accent-soft);outline:1.5px solid var(--accent);font-weight:700}.rush__box-aa{font-weight:600}.rush__box-aa:before{content:"";background:var(--aa);vertical-align:.05em;border-radius:50%;width:.55em;height:.55em;margin-right:.25em;display:inline-block}.rush__box-aa.is-stop{color:var(--danger)}.rush__box-aa.is-stop:before{display:none}.rush__cards{grid-template-columns:repeat(var(--rush-cols,4), minmax(0, 1fr));gap:.5rem;margin-top:.6rem;display:grid;position:relative}.rush__card{border:2px solid color-mix(in srgb, var(--rush-pink) 45%, var(--border));background:color-mix(in srgb, var(--rush-pink) 7%, var(--surface));min-width:0;min-height:4.9rem;color:var(--text);font:inherit;cursor:pointer;touch-action:manipulation;-webkit-tap-highlight-color:transparent;border-radius:12px;flex-direction:column;justify-content:center;align-items:center;gap:.35rem;padding:.5rem .3rem;transition:transform 80ms ease-out,background .15s,border-color .15s,opacity .2s;animation:.3s ease-out rush-card-in;display:flex;position:relative}.rush__card:hover:not(:disabled){background:color-mix(in srgb, var(--rush-pink) 15%, var(--surface));border-color:var(--rush-pink)}.rush__card:active:not(:disabled){transform:scale(.95)}.rush__card:focus-visible{outline:3px solid var(--accent);outline-offset:2px}.rush__card:disabled{cursor:default}.rush[data-phase=intro] .rush__card,.rush[data-phase=auto] .rush__card{opacity:.45}.rush__card.is-tried{opacity:.42;border-style:dashed;border-color:var(--rush-bad)}.rush__card.is-tried:after{content:"✕";color:var(--rush-bad);font-weight:800;position:absolute;top:.15rem;right:.45rem}.rush__card--rf{border-color:color-mix(in srgb, var(--rush-rf) 55%, var(--border));background:color-mix(in srgb, var(--rush-rf) 9%, var(--surface))}.rush__card--rf:hover:not(:disabled){border-color:var(--rush-rf);background:color-mix(in srgb, var(--rush-rf) 17%, var(--surface))}.rush__card.is-shake{animation:.4s ease-in-out rush-shake}.rush__key{color:var(--muted);font-size:.72rem;font-weight:700;position:absolute;top:.2rem;left:.45rem}.rush__card-top{align-items:center;gap:.3rem;display:inline-flex}.rush__icon{width:1.05rem;height:1.3rem;color:var(--rush-pink);flex:none}.rush__card-name{font-size:.95rem;font-weight:700}.rush__card-sub{color:var(--muted);font-size:.75rem}.rush__line--card .rush__tile{width:1.55rem;height:1.6rem;font-size:.95rem}.rush__cards--many .rush__line--card{gap:.12rem}.rush__cards--many .rush__line--card .rush__letters{gap:2px}.rush__cards--many .rush__line--card .rush__tile{border-radius:5px;width:1.35rem;height:1.5rem;font-size:.88rem}.rush__cards--many .rush__line--card .rush__end{min-width:0;font-size:.66rem}.rush__bead{color:#0f172a;background:radial-gradient(circle at 35% 30%, #fff 0%, var(--aa) 48%, color-mix(in srgb, var(--aa) 70%, #000) 100%);border-radius:50%;flex:none;place-items:center;font-weight:800;display:inline-grid;box-shadow:0 1px 3px #0000004d}.rush__bead--md{width:1.75rem;height:1.75rem;font-size:.95rem}.rush__stop{clip-path:polygon(30% 0,70% 0,100% 30%,100% 70%,70% 100%,30% 100%,0 70%,0 30%);background:var(--rush-rf);color:#fff;place-items:center;width:2.1rem;height:2.1rem;font-size:.66rem;font-weight:800;display:inline-grid}@media (prefers-color-scheme:dark){.rush__stop{color:#2e1065}}.rush__startbar{flex-wrap:wrap;align-items:center;gap:.4rem .8rem;margin-top:.6rem;font-size:.88rem;display:flex}.rush__startbar .button{min-height:2.75rem;padding-inline:1.4em}.rush__note{margin-top:.6rem}.rush__result p{margin:.3rem 0 .6rem}.rush__headline{font-size:1.15rem}.rush__stats{font-size:.85rem}.rush__after{margin-top:.4rem}.rush__speeds{gap:.3rem;margin:.2rem 0 .7rem;font-size:.85rem;display:grid}.rush__speed{font-variant-numeric:tabular-nums;grid-template-columns:7.5rem minmax(0,1fr) 6.5rem;align-items:center;gap:.5rem;display:grid}.rush__bar{background:var(--surface);border-radius:999px;height:.8rem;position:relative;overflow:hidden}.rush__bar span{background:var(--accent);border-radius:999px;position:absolute;inset:0 auto 0 0}.rush__speed:first-child .rush__bar span{background:var(--c-swe)}.rush__bar .rush__bar-low{background:#ffffff59}.rush__protein{background:var(--surface-2);border-radius:10px;margin-top:.7rem;padding:.5rem .7rem .4rem}.rush__protein-head{flex-wrap:wrap;align-items:baseline;gap:.2rem .7rem;font-size:.85rem;display:flex}.rush__chain{flex-wrap:wrap;gap:2px;margin:.35rem 0 .2rem;display:flex}.rush__chain-bead{color:#0f172a;background:radial-gradient(circle at 35% 30%, #fff 0%, var(--aa) 50%, color-mix(in srgb, var(--aa) 72%, #000) 100%);border-radius:50%;place-items:center;width:1.45rem;height:1.45rem;font-size:.78rem;font-weight:800;animation:.35s cubic-bezier(.34,1.56,.64,1) rush-bead-in;display:inline-grid}.rush__match{margin:.3rem 0;font-size:.82rem}.rush__match.is-good{color:var(--success)}.rush__seq{word-break:break-all;font-size:.85em}.rush__legend{color:var(--muted);flex-wrap:wrap;gap:.15rem .9rem;margin:.25rem 0 0;padding:0;font-size:.78rem;list-style:none;display:flex}.rush__legend li+li{margin-top:0}.rush__dot{vertical-align:-.05em;border-radius:50%;width:.7em;height:.7em;display:inline-block}.rush__tools{margin-top:.7rem}.rush__toggle.is-on{border-color:var(--accent);background:var(--accent-soft)}.rush__table{border:1px solid var(--border);border-radius:10px;margin-top:.6rem;padding:.6rem .7rem .7rem}.rush__table-head{flex-wrap:wrap;justify-content:space-between;align-items:center;gap:.4rem .8rem;display:flex}.rush__table-help{margin:.3rem 0 .5rem;font-size:.8rem}.rush__seg{border:1px solid var(--border);border-radius:999px;display:inline-flex;overflow:hidden}.rush__seg button{font:inherit;background:var(--bg);color:var(--text);cursor:pointer;border:0;padding:.35em .8em;font-size:.78rem;font-weight:600}.rush__seg button.is-active{background:var(--accent);color:var(--accent-text)}.rush__grid{grid-template-columns:auto repeat(4,minmax(0,1fr));gap:3px;display:grid}.rush__grid-row{display:contents}.rush__grid-head{font-family:var(--font-mono);color:var(--base);place-items:center;padding:0 .25rem;font-weight:800;display:grid}.rush__grid-corner{color:var(--muted);align-self:end;font-size:.62rem;line-height:1.2}.rush__grid .rush__box{background:var(--surface-2);border-radius:6px;justify-self:stretch;padding:.15rem 0}.rush__box--compact .rush__box-line{gap:.25rem;padding:0 .25rem;font-size:.74rem}.rush__scale{margin:.7rem 0 0;font-size:.8rem}@keyframes rush-shake{0%,to{transform:translate(0)}20%{transform:translate(-6px)}40%{transform:translate(6px)}60%{transform:translate(-4px)}80%{transform:translate(4px)}}@keyframes rush-card-in{0%{opacity:.2;transform:translateY(6px)scale(.96)}}@keyframes rush-bead-in{0%{transform:scale(.3)}}@media (prefers-reduced-motion:reduce){.rush__card,.rush__card.is-shake,.rush__chain-bead{animation:none}}@media (width<=640px){.rush .rush__stage{height:clamp(320px,90vw,370px)}.rush .rush__intro{padding:.6rem .7rem}.rush__intro h4{margin-bottom:.35rem;font-size:1.08rem}.rush__intro p{margin-bottom:.45rem;font-size:.85rem;line-height:1.42}.rush__diagram{gap:.2rem .4rem;margin-bottom:.45rem;padding:.3rem .6rem}.rush__intro .rush__tile{width:1.4rem;height:1.45rem;font-size:.85rem}.rush__cards{grid-template-columns:repeat(var(--rush-cols-phone,3), minmax(0, 1fr));gap:.4rem}.rush__card{gap:.3rem;min-height:4.5rem;padding:.45rem .2rem .4rem}.rush__card-name{font-size:.88rem}.rush__icon{display:none}.rush__line--card{gap:.1rem}.rush__line--card .rush__letters{gap:2px}.rush__line--card .rush__tile{border-radius:5px;width:1.3rem;height:1.45rem;font-size:.88rem}.rush__line--card .rush__end{min-width:0;font-size:.62rem}.rush__decoder{grid-template-columns:auto auto auto;justify-content:space-between;gap:.35rem;padding:.4rem .5rem}.rush__count{font-size:.78rem}.rush__tile{width:1.6rem;height:1.65rem;font-size:.98rem}.rush__box{font-size:.72rem}.rush__speed{grid-template-columns:5.6rem minmax(0,1fr) 5.2rem;font-size:.8rem}.rush__grid-corner{visibility:hidden}.rush__grid{grid-template-columns:1.1rem repeat(4,minmax(0,1fr));gap:2px}.rush__box--compact .rush__box-line{gap:.15rem;padding:0 .15rem;font-size:.68rem}}@media (pointer:coarse){.rush .game__level,.rush .game__sound,.rush__seg button{min-height:2.75rem}}.factory{--factory-mrna:#db2777;--factory-protein:#d97706;--factory-goal:#15803d;--factory-ghost:#94a3b8;--factory-chart-bg:var(--bg)}@media (prefers-color-scheme:dark){.factory{--factory-mrna:#f472b6;--factory-protein:#fbbf24;--factory-goal:#4ade80;--factory-ghost:#64748b}}.factory__play{grid-template-columns:minmax(0,1fr) minmax(0,1fr);gap:.6rem;display:grid;position:relative}.factory__intro{overscroll-behavior:auto;background:#0b1220e6;border-radius:10px}.factory__stage{aspect-ratio:1;-webkit-user-select:none;user-select:none}.factory__stage canvas,.factory__chart canvas{width:100%;height:100%;display:block;position:absolute;inset:0}.factory__charts{grid-template-rows:minmax(0,1fr) minmax(0,1fr);gap:.6rem;min-height:0;display:grid}.factory__chart{border:1px solid var(--border);background:var(--factory-chart-bg);border-radius:10px;min-height:0;position:relative;overflow:hidden}.factory__hist{height:150px;margin-top:.7rem}.factory__stage .game__toast{width:max-content;max-width:90%}.factory__stage .game__chip{pointer-events:none;font-variant-numeric:tabular-nums;font-size:.82rem}.factory__clock{align-items:center;gap:.45rem;padding:.25rem .6rem .25rem .35rem;display:flex}.factory__clock svg{flex:none;display:block}.factory__clock strong{font-size:1.05rem}.factory__clock small{opacity:.8;font-size:.75rem}.factory__counts{flex-direction:column;align-items:flex-end;gap:.05rem;display:flex}.factory__counts span{white-space:nowrap;align-items:center;gap:.35em;display:inline-flex}.factory__counts strong{text-align:right;min-width:2.2em}.factory__daughters .game__chip{white-space:nowrap;font-size:.8rem}.factory__key{vertical-align:-.05em;border-radius:50%;flex:none;width:.8em;height:.8em;display:inline-block}.factory__key--gene{background:#a3e635;border-radius:999px;width:1.1em;height:.38em;box-shadow:0 0 0 2px #a3e63540}.factory__key--rnap{background:radial-gradient(circle at 35% 35%,#f0f9ff,#38bdf8 55%,#0c4a6e)}.factory__key--mrna{background:#f472b6;border-radius:999px;width:1.2em;height:.32em}.factory__key--ribo{background:radial-gradient(circle at 35% 35%,#f5f3ff,#8b5cf6 55%,#3b0764);width:1em}.factory__key--protein{background:radial-gradient(circle at 35% 35%,#fffbeb,#f59e0b 60%,#b45309);width:.62em;height:.62em}.factory__key--band{border-top:2px dashed var(--muted);background:#94a3b847;border-radius:3px;width:1.3em;height:.7em}.factory__legend{color:var(--muted);flex-wrap:wrap;gap:.25rem 1rem;margin:.55rem 0 0;padding:0;font-size:.85rem;list-style:none;display:flex}.factory__legend li{align-items:center;gap:.4em;margin:0;display:inline-flex}.factory__note,.factory__fine{color:var(--muted);margin:.35rem 0 0;font-size:.83rem}.factory__intro h4{margin-bottom:.4rem}.factory__intro p{margin-bottom:.55rem;line-height:1.5}.factory__choices{justify-content:center;margin-bottom:.6rem}.factory__choices .button{justify-content:center;min-width:4.2rem;min-height:44px}.factory__choices .button.is-right{color:#fff;opacity:1;background:#16a34a;border-color:#16a34a}.factory__choices .button.is-wrong{text-decoration:line-through}.factory__answer{font-weight:600}.factory__answer.is-good{color:#86efac}.factory__answer.is-bad{color:#fca5a5}.factory__intro .button--primary{min-height:44px}.factory__rule{color:#cbd5e1;margin-top:.8rem;font-size:.8rem}.factory__bar{flex-wrap:wrap;align-items:center;gap:.5rem;margin-top:.75rem;display:flex}.factory__bar .button{min-height:44px}.factory__run{justify-content:center;min-width:7.5rem}.factory__progress{margin:.7rem 0 0;font-size:.95rem}.factory__sliders{grid-template-columns:repeat(2,minmax(0,1fr));gap:.7rem 1.2rem;margin-top:1rem;display:grid}.factory__slider{min-width:0}.factory__slider-head{flex-wrap:wrap;justify-content:space-between;align-items:baseline;gap:0 .6rem;font-size:.92rem;display:flex}.factory__slider-head label{font-weight:600}.factory__slider-head output{font-variant-numeric:tabular-nums;color:var(--text)}.factory__slider-row{align-items:center;gap:.4rem;display:flex}.factory__step{border:1px solid var(--border);background:var(--surface);width:2.25rem;height:2.25rem;color:var(--text);font:inherit;cursor:pointer;border-radius:50%;flex:none;font-size:1.25rem;font-weight:600;line-height:1}.factory__step:hover:not(:disabled){border-color:var(--accent)}.factory__step:disabled{opacity:.4;cursor:not-allowed}.factory__range{-webkit-appearance:none;appearance:none;cursor:pointer;background:0 0;flex:auto;min-width:0;height:2.5rem;margin:0}.factory__range:disabled{cursor:not-allowed}.factory__range::-webkit-slider-runnable-track{background:linear-gradient(to right, var(--knob) 0 var(--fill), var(--border) var(--fill) 100%);border-radius:999px;height:10px}.factory__range::-webkit-slider-thumb{-webkit-appearance:none;appearance:none;background:var(--surface);border:3px solid var(--knob);border-radius:50%;width:26px;height:26px;margin-top:-8px;box-shadow:0 1px 4px #0000004d}.factory__range::-moz-range-track{background:var(--border);border-radius:999px;height:10px}.factory__range::-moz-range-progress{background:var(--knob);border-radius:999px;height:10px}.factory__range::-moz-range-thumb{background:var(--surface);border:3px solid var(--knob);border-radius:50%;width:22px;height:22px;box-shadow:0 1px 4px #0000004d}.factory__range:focus-visible{outline:2px solid var(--accent);outline-offset:2px;border-radius:6px}.factory__slider.is-locked{opacity:.55}.factory__slider-note{color:var(--muted);margin:0;font-size:.8rem}.factory__math{background:var(--surface-2);border-radius:9px;margin-top:1rem;padding:.75rem .9rem .6rem}.factory__math-title{margin:0 0 .35rem;font-weight:700}.factory__math-title span{color:var(--muted);font-size:.85rem;font-weight:400}.factory__math dl{gap:.25rem;margin:0;display:grid}.factory__math dl>div{grid-template-columns:minmax(0,15rem) minmax(0,1fr);gap:.6rem;font-size:.92rem;display:grid}.factory__math dt{color:var(--muted)}.factory__math dd{font-variant-numeric:tabular-nums;margin:0}.factory__math dd strong{color:var(--accent)}@media (pointer:coarse){.factory .game__level,.factory .game__sound,.factory .game__feedback .button{min-height:44px}.factory__step{width:44px;height:44px}.factory__range{height:44px}.factory__range::-webkit-slider-thumb{width:32px;height:32px;margin-top:-11px}.factory__range::-moz-range-thumb{width:28px;height:28px}}@media (width<=639px){.factory__play{grid-template-columns:minmax(0,1fr);gap:.45rem}.factory__stage{aspect-ratio:11/10}.factory__charts{grid-template-rows:100px 100px;gap:.45rem}.factory__stage .game__chip{font-size:.76rem}.factory__daughters .game__chip{padding:.3rem .45rem;font-size:.72rem}.factory__sliders{grid-template-columns:minmax(0,1fr)}.factory__bar .button{flex:auto;justify-content:center}.factory__math dl>div{grid-template-columns:minmax(0,1fr);gap:0}.factory__hist{height:140px}}@media (prefers-reduced-motion:reduce){.factory__choices .button{transition:none}}.mut__mission{background:var(--surface-2);border-radius:10px;margin-bottom:.7rem;padding:.6rem .85rem .65rem;font-size:.95rem}.mut__goal{margin:0 0 .35rem;line-height:1.45}.mut__steps{gap:.3rem;margin:.2rem 0 .5rem;padding:0;list-style:none;display:grid}.mut__steps li{align-items:flex-start;gap:.5rem;margin:0;line-height:1.4;display:flex}.mut__check{border:2px solid var(--border);background:var(--bg);color:#fff;border-radius:50%;flex:none;place-items:center;width:1.35rem;height:1.35rem;font-size:.8rem;font-weight:800;display:inline-grid}.mut__steps li.is-done .mut__check{border-color:var(--success);background:var(--success)}.mut__steps li.is-done{color:var(--muted)}.mut__mission-row{flex-wrap:wrap;align-items:center;gap:.45rem .8rem;display:flex}.mut__tip{flex:12rem;font-size:.88rem;line-height:1.4}.mut__hint-btn.is-on{border-color:var(--accent);background:var(--accent-soft)}.mut__hint{border-left:3px solid var(--c-swe);background:var(--surface);border-radius:6px;margin:.5rem 0 0;padding:.45rem .65rem;font-size:.9rem;line-height:1.45}.mut__code{border:1px solid var(--border);background:var(--bg);border-radius:999px;flex-wrap:wrap;align-items:center;gap:3px;padding:3px;display:inline-flex}.mut__code-label{color:var(--muted);padding:0 .4rem 0 .55rem;font-size:.78rem;font-weight:700}.mut__code-btn{font:inherit;min-height:2.4rem;color:var(--text);cursor:pointer;touch-action:manipulation;background:0 0;border:0;border-radius:999px;padding:.3em .9em;font-size:.86rem;font-weight:650}.mut__code-btn.is-on{background:var(--accent);color:var(--accent-text)}.mut__code-btn:focus-visible,.mut__mode:focus-visible,.mut__tile:focus-visible,.mut__zl:focus-visible,.mut__key:focus-visible,.mut__step:focus-visible{outline:2px solid var(--accent);outline-offset:2px}.mut .mut__stage{color:#e2e8f0;background:radial-gradient(130% 120% at 15% 0,#1b2a47 0%,#0b1220 55%,#070b14 100%);border:1px solid #94a3b82e}.mut .mut__stage.is-intro{min-height:370px}.mut__stage-head{color:#cbd5e1;flex-wrap:wrap;justify-content:space-between;align-items:center;gap:.3rem .6rem;padding:.55rem .8rem 0;font-size:.8rem;line-height:1.35;display:flex}.mut__gene strong{color:#f8fafc;font-size:.92rem;font-style:italic}.mut__codechip{color:#bbf7d0;background:#22c55e2e;border:1px solid #4ade808c;border-radius:999px;padding:.15rem .6rem;font-size:.74rem;font-weight:700}.mut__codechip.is-std{color:#fed7aa;background:#f973162e;border-color:#fb923c99}.mut__strip{overscroll-behavior-x:contain;scrollbar-width:thin;scrollbar-color:#475569 transparent;position:relative;overflow:auto hidden}.mut__strip::-webkit-scrollbar{height:6px}.mut__strip::-webkit-scrollbar-thumb{background:#475569;border-radius:3px}.mut__track{padding:24px 14px 4px;position:relative}.mut__row{display:flex}.mut__prime{font:700 10px/1 var(--font-body);color:#94a3b8;position:absolute;top:34px}.mut__prime--5{left:1px}.mut__prime--3{right:1px}.mut__col,.mut__cell{flex:0 0 var(--mut-col);width:var(--mut-col)}.mut__tile{height:50px;color:inherit;font:inherit;cursor:pointer;touch-action:manipulation;-webkit-tap-highlight-color:transparent;background:0 0;border:0;flex-direction:column;align-items:center;padding:0;display:flex;position:relative}.mut__tile:disabled{cursor:default}.mut__letters{background:linear-gradient(#1f2b40,#111827);border:1px solid #94a3b84d;border-radius:8px;gap:1px;padding:2px;transition:box-shadow .15s,border-color .15s;display:flex;box-shadow:0 2px 6px #0006}.mut__tile:hover:not(:disabled) .mut__letters{border-color:#e2e8f0b3}.mut__base{background:linear-gradient(180deg, color-mix(in srgb, var(--base) 88%, #fff) 0%, var(--base) 45%, color-mix(in srgb, var(--base) 70%, #000) 100%);width:12px;height:34px;font:800 13px/1 var(--font-mono);color:#fff;text-shadow:0 1px 2px #0009;border-radius:4px;place-items:center;transition:transform .15s;display:grid;position:relative}.mut__base-letter{z-index:1;position:relative}.mut__base-letter.is-zapped{animation:.6s ease-out mut-flash}.mut__ruler{font:600 9.5px/1 var(--font-body);color:#94a3b8;text-shadow:none;white-space:nowrap;position:absolute;top:-19px;left:50%;transform:translate(-50%)}.mut__ruler:after{content:"";background:#64748b;width:1px;height:4px;position:absolute;top:11px;left:50%}.mut__base.is-sub:after{content:"";z-index:2;background:#fde047;border-radius:50%;width:7px;height:7px;position:absolute;top:-4px;right:-3px;box-shadow:0 0 6px 1px #fde047}.mut__base.is-ins{outline-offset:-1px;outline:2px dashed #f8fafc}.mut__base.is-ins:after{content:"+";color:#0b1220;width:11px;height:11px;font:900 10px/1 var(--font-body);text-shadow:none;z-index:2;background:#f8fafc;border-radius:50%;place-items:center;display:grid;position:absolute;top:-8px;right:-5px}.mut__base.has-del:before,.mut__enddel:before{content:"";z-index:2;border:4px solid #0000;border-top:7px solid #fb7185;position:absolute;top:-10px;left:-4px;transform:translate(-50%)}.mut__base.has-del{box-shadow:-2.5px 0 #fb7185}.mut__enddel{border-left:2.5px solid #fb7185;width:6px;height:34px;margin-top:3px;position:relative}.mut__base.is-sel{z-index:3;transform:translateY(-3px);box-shadow:0 0 0 2px #fff,0 3px 8px #00000080}.mut__bracket{border:2px solid #94a3b880;border-top:0;border-radius:0 0 4px 4px;width:36px;height:6px;margin-top:4px;display:block}.mut__tile.is-selected .mut__letters{border-color:#fbbf24;box-shadow:0 0 0 2px #fbbf24,0 0 16px #fbbf248c}.mut__tile.is-selected .mut__bracket{border-color:#fbbf24}.mut__tile.is-start .mut__bracket{border-color:#4ade80}.mut__tile.is-shifted .mut__letters{background:repeating-linear-gradient(135deg,#a855f78c 0 4px,#2e1065f2 4px 8px);border-color:#c084fcd9}.mut__tile.is-shifted .mut__bracket{border-color:#c084fc}.mut__tile.is-stop .mut__letters{border-color:#f87171;box-shadow:0 0 0 1px #f87171,0 0 14px #f8717199}.mut__tile.is-stop .mut__bracket{border-color:#f87171}.mut__tile.is-unread{opacity:.38;filter:saturate(.35)}.mut__tile.is-unread.is-selected{opacity:.75}.mut__zap{pointer-events:none;z-index:4;width:0;height:0;position:absolute;top:50%;left:50%}.mut__bolt{fill:#fde047;filter:drop-shadow(0 0 3px #fde047)drop-shadow(0 0 8px #f59e0b);width:16px;height:27px;animation:.65s ease-out forwards mut-bolt;position:absolute;top:-40px;left:-8px}.mut__burst{border:2px solid #fde047;border-radius:50%;width:34px;height:34px;animation:.6s ease-out forwards mut-burst;position:absolute;top:-17px;left:-17px;box-shadow:0 0 12px #fde047,inset 0 0 8px #fde047}.mut__zap--ins .mut__bolt{fill:#a7f3d0;filter:drop-shadow(0 0 3px #6ee7b7)drop-shadow(0 0 8px #10b981)}.mut__zap--ins .mut__burst{border-color:#6ee7b7;box-shadow:0 0 12px #6ee7b7,inset 0 0 8px #6ee7b7}.mut__zap--del .mut__bolt{fill:#fecdd3;filter:drop-shadow(0 0 3px #fb7185)drop-shadow(0 0 8px #e11d48)}.mut__zap--del .mut__burst{border-color:#fb7185;left:-24px;box-shadow:0 0 12px #fb7185,inset 0 0 8px #fb7185}@keyframes mut-bolt{0%{opacity:0;transform:translateY(-10px)scaleY(.5)}14%{opacity:1;transform:translateY(0)scaleY(1)}28%{opacity:.3}42%{opacity:1}to{opacity:0;transform:translateY(4px)}}@keyframes mut-burst{0%{opacity:1;transform:scale(.2)}to{opacity:0;transform:scale(1.7)}}@keyframes mut-flash{0%{text-shadow:0 0 6px #fff,0 0 14px #fde047;transform:scale(1.7)}to{transform:scale(1)}}.mut__row--beads{height:46px;margin-top:4px;position:relative}.mut__backbone{pointer-events:none;position:absolute;top:0;left:0;overflow:visible}.mut__chain{fill:none;stroke:#cbd5e1;stroke-width:4px;stroke-linecap:round;opacity:.5}.mut__chain--ghost{stroke-dasharray:2 7;opacity:.3}.mut__cell{place-items:center;display:grid;position:relative}.mut__bead,.mut__mini{color:#fff;text-shadow:0 1px 2px #0000008c;font-family:var(--font-body);border-radius:50%;place-items:center;font-weight:800;line-height:1;display:grid;position:relative}.mut__bead{width:34px;height:34px;animation:.45s cubic-bezier(.3,1.6,.5,1) both mut-pop;animation-delay:calc(var(--d,0) * 22ms);font-size:14px;box-shadow:inset -3px -4px 6px #00000040,0 3px 6px #00000073}.mut__bead>span,.mut__mini>span{z-index:1;position:relative}.mut__bead.is-up{translate:0 -3px}.mut__bead.is-down{translate:0 3px}.mut__bead:after,.mut__mini--lg:after{content:"";background:#ffffff8c;border-radius:50%;width:34%;height:18%;position:absolute;top:14%;left:22%;transform:rotate(-30deg)}.mut__bead--oily{background:radial-gradient(circle at 35% 30%,#fff7d6 0%,#fcd34d 28%,#f59e0b 64%,#b45309 100%)}.mut__bead--polar{background:radial-gradient(circle at 35% 30%,#e0f2fe 0%,#7dd3fc 28%,#0ea5e9 64%,#075985 100%)}.mut__bead--plus{background:radial-gradient(circle at 35% 30%,#ede9fe 0%,#a78bfa 28%,#7c3aed 64%,#4c1d95 100%)}.mut__bead--minus{background:radial-gradient(circle at 35% 30%,#ffe4e6 0%,#fb7185 28%,#e11d48 64%,#881337 100%)}.mut__bead--stop{clip-path:polygon(29% 0,71% 0,100% 29%,100% 71%,71% 100%,29% 100%,0 71%,0 29%);letter-spacing:.02em;background:linear-gradient(#f87171,#b91c1c);border-radius:0;font-size:8.5px}.mut__bead.mut__bead--stop{width:36px;height:36px}.mut__bead--stop:after{display:none}.mut__bead--ghost{color:#94a3b8bf;text-shadow:none;box-shadow:none;background:0 0;border:1.5px dashed #94a3b880}.mut__bead.mut__bead--ghost{animation-name:mut-fade}.mut__bead--ghost:after{display:none}.mut__bead--ghost-stop{border-radius:6px;font-size:7.5px}.mut__bead.is-changed:before{content:"";border:3px solid #fde047;border-radius:50%;animation:1.8s ease-in-out infinite mut-ring;position:absolute;inset:-5px;box-shadow:0 0 10px 1px #fde047bf}.mut__more{color:#93c5fd;font-size:.95rem;font-weight:800}@keyframes mut-pop{0%{opacity:0;transform:scale(.3)}60%{opacity:1;transform:scale(1.18)}to{transform:scale(1)}}@keyframes mut-fade{0%{opacity:0}}@keyframes mut-ring{0%,to{opacity:1}50%{opacity:.45}}.mut__row--nums{height:17px}.mut__num{color:#94a3b8;text-align:center;font-size:10px;line-height:17px}.mut__was{color:#fde047;white-space:nowrap;font-weight:700}.mut__map{touch-action:pan-y;cursor:pointer;-webkit-user-select:none;user-select:none;margin:0 .8rem;padding:.35rem 0 .3rem}.mut__map-label{color:#cbd5e1;justify-content:space-between;gap:.5rem;margin-bottom:.25rem;font-size:.8rem;line-height:1.3;display:flex}.mut__map-label strong{color:#f8fafc;font-variant-numeric:tabular-nums;font-size:1rem}.mut__map-label strong.is-short{color:#fca5a5}.mut__map-changed{color:#fde047;font-weight:700}.mut__map-bar{background:#0f172a;border:1px solid #94a3b84d;border-radius:6px;width:100%;height:22px;display:block}.mut__seg{transition:fill .4s}.mut__seg.is-oily{fill:#f59e0b}.mut__seg.is-polar{fill:#0ea5e9}.mut__seg.is-plus{fill:#8b5cf6}.mut__seg.is-minus{fill:#e11d48}.mut__seg.is-changed{fill:#fde047}.mut__seg.is-stop{fill:#ef4444}.mut__seg.is-lost{fill:#94a3b824}.mut__seg.is-empty{fill:#0000}.mut__map-window{fill:#ffffff1f;stroke:#f8fafc;stroke-width:1.5px;vector-effect:non-scaling-stroke}.mut__legend{color:#cbd5e1;flex-wrap:wrap;gap:.25rem .85rem;padding:.45rem .8rem .6rem;font-size:.74rem;line-height:1.5;display:flex}.mut__legend>span{align-items:center;gap:.3rem;display:inline-flex}.mut__mini{vertical-align:middle;flex:none;width:18px;height:18px;font-size:10px}.mut__mini--lg{width:44px;height:44px;font-size:19px;box-shadow:inset -3px -4px 6px #00000040,0 3px 6px #0000004d}.mut__mini.mut__bead--stop>span{font-size:0}.mut__mini--lg.mut__bead--stop>span,.mut__mini.mut__bead--ghost{font-size:9px}.mut__swatch{border-radius:50%;width:16px;height:16px;display:inline-block}.mut__swatch--changed{border:3px solid #fde047;box-shadow:0 0 6px #fde047cc}.mut__swatch--shifted{background:repeating-linear-gradient(135deg,#a855f7cc 0 3px,#2e1065 3px 6px);border:1px solid #c084fc;border-radius:4px}.mut .game__toast{z-index:6;white-space:nowrap;top:calc(100% - 46px);box-shadow:0 6px 18px #00000073}.mut__toast--none{background:#475569f2}.mut__toast--good,.mut__toast--silent,.mut__toast--whole{background:#16a34af0}.mut__toast--missense,.mut__toast--inframe{background:#d97706f2}.mut__toast--bad,.mut__toast--nonsense,.mut__toast--cut{background:#dc2626f0}.mut__toast--frameshift{background:#7c3aedf2}.mut__toast--restored{background:#0d9488f2}.mut__toast--readthrough{background:#2563ebf2}.mut__toast--twist{background:#db2777f2}.mut__intro{z-index:5}.mut__intro h4{color:#fde047}.mut__intro p{font-size:.95rem;line-height:1.5}.mut__intro-how{color:#cbd5e1;font-style:italic}.mut__verdict,.mut__badge--none{--vcol:#64748b}.mut__verdict--silent,.mut__verdict--whole,.mut__badge--silent,.mut__badge--whole{--vcol:#16a34a}.mut__verdict--missense,.mut__verdict--inframe,.mut__badge--missense,.mut__badge--inframe{--vcol:#d97706}.mut__verdict--nonsense,.mut__verdict--cut,.mut__badge--nonsense,.mut__badge--cut{--vcol:#dc2626}.mut__verdict--frameshift,.mut__badge--frameshift{--vcol:#7c3aed}.mut__verdict--restored,.mut__badge--restored{--vcol:#0d9488}.mut__verdict--readthrough,.mut__badge--readthrough{--vcol:#2563eb}.mut__verdict{border-left:5px solid var(--vcol);background:color-mix(in srgb, var(--vcol) 10%, var(--surface));border-radius:10px;margin-top:.7rem;padding:.55rem .8rem .6rem;font-size:.93rem;line-height:1.45}.mut__verdict-top{flex-wrap:wrap;align-items:center;gap:.3rem .55rem;display:flex}.mut__badge{background:var(--vcol);color:#fff;letter-spacing:.06em;text-transform:uppercase;white-space:nowrap;border-radius:999px;padding:.2em .6em;font-size:.72rem;font-weight:800;display:inline-block}.mut__badge--sm{vertical-align:.1em;padding:.15em .5em;font-size:.66rem}.mut__headline{font-size:1rem}.mut__detail{margin:.25rem 0 0}.mut__other{border-top:1px dashed var(--border);margin:.4rem 0 0;padding-top:.4rem;font-size:.88rem}.mut__note{background:var(--danger-soft);border-radius:7px;margin:.45rem 0 0;padding:.4rem .6rem;font-size:.9rem}.mut__done p{margin:.3rem 0 .55rem}.mut__end-note{font-size:.85rem}.mut__zoom{border:1px solid var(--border);background:var(--surface-2);border-radius:12px;margin-top:.7rem;padding:.65rem .8rem .7rem}.mut__zoom-empty{color:var(--muted);align-items:center;gap:.6rem;margin:.1rem 0 .6rem;font-size:.93rem;display:flex}.mut__lens{border:3px solid var(--accent);border-radius:50%;flex:none;width:26px;height:26px;position:relative}.mut__lens:after{content:"";background:var(--accent);border-radius:2px;width:10px;height:4px;position:absolute;bottom:-6px;right:-9px;transform:rotate(45deg)}.mut__zoom-head{flex-wrap:wrap;justify-content:space-between;gap:.2rem .8rem;margin-bottom:.45rem;font-size:.88rem;display:flex}.mut__zoom-main{flex-wrap:wrap;align-items:center;gap:.45rem;display:flex}.mut__step{border:1px solid var(--border);background:var(--bg);width:2.75rem;height:3.6rem;color:var(--text);font:inherit;cursor:pointer;touch-action:manipulation;border-radius:10px;font-size:1.6rem;line-height:1}.mut__step:disabled{opacity:.4;cursor:default}.mut__zoom-letters{gap:.3rem;display:flex}.mut__zl{--base:#64748b;border:2px solid var(--base);background:color-mix(in srgb, var(--base) 16%, var(--surface));width:3.3rem;height:3.6rem;color:var(--text);font:inherit;cursor:pointer;touch-action:manipulation;border-radius:10px;flex-direction:column;justify-content:center;align-items:center;transition:transform .1s,background .15s;display:flex}.mut__zl-letter{font:800 1.6rem/1 var(--font-mono);color:color-mix(in srgb, var(--base) 80%, #000)}.mut__zl-pos{color:var(--muted);margin-top:.15rem;font-size:.68rem}.mut__zl.is-sel{background:var(--base);box-shadow:0 4px 10px color-mix(in srgb, var(--base) 45%, transparent);transform:translateY(-2px)}.mut__zl.is-sel .mut__zl-letter,.mut__zl.is-sel .mut__zl-pos{color:#fff;text-shadow:0 1px 2px #0006}.mut__zoom-arrow{color:var(--muted);font-size:1.3rem}.mut__zoom-aa{align-items:center;gap:.5rem;font-size:.92rem;line-height:1.3;display:flex}.mut__zoom-aa>span:last-child{flex-direction:column;display:flex}.mut__zoom-was{color:var(--c-swe);font-size:.8rem;font-weight:600}.mut__modes{border:1px solid var(--border);background:var(--bg);border-radius:10px;gap:3px;margin-top:.6rem;padding:3px;display:inline-flex}.mut__mode{font:inherit;min-width:5.2rem;min-height:2.6rem;color:var(--text);cursor:pointer;touch-action:manipulation;background:0 0;border:0;border-radius:8px;padding:.3em .8em;font-size:.9rem;font-weight:650}.mut__mode.is-on{background:var(--accent);color:var(--accent-text)}.mut__actions{margin-top:.55rem}.mut__action-label{margin:0 0 .35rem;font-size:.9rem}.mut__pad{grid-template-columns:repeat(4,minmax(0,1fr));gap:.45rem;max-width:26rem;display:grid}.mut__key{--base:#64748b;border:2px solid var(--base);background:color-mix(in srgb, var(--base) 16%, var(--surface));min-height:3.5rem;color:var(--text);font:inherit;cursor:pointer;touch-action:manipulation;border-radius:12px;flex-direction:column;justify-content:center;align-items:center;gap:.1rem;padding:.3rem .2rem;transition:transform 80ms ease-out,background .15s;display:flex}.mut__key:hover:not(:disabled){background:color-mix(in srgb, var(--base) 30%, var(--surface))}.mut__key:active:not(:disabled){transform:scale(.94)}.mut__key:disabled{opacity:.45;cursor:default;border-style:dashed}.mut__key-letter{font:800 1.45rem/1 var(--font-mono);color:color-mix(in srgb, var(--base) 80%, #000)}.mut__key-name{color:var(--muted);font-size:.72rem}.mut__key--delete{--base:#dc2626;grid-column:span 2}.mut__locked{background:var(--surface);border-left:3px solid #22c55e;border-radius:8px;margin:.55rem 0 0;padding:.45rem .65rem;font-size:.88rem;line-height:1.45}.mut__table{color:var(--muted);flex-wrap:wrap;align-items:center;gap:.3rem .6rem;margin-top:.6rem;font-size:.8rem;display:flex}.mut__table-row{flex-wrap:wrap;gap:.3rem;display:flex}.mut__table-cell{border:1px solid var(--border);background:var(--surface);color:var(--text);border-radius:7px;align-items:center;gap:.25rem;padding:.12rem .4rem .12rem .3rem;display:inline-flex}.mut__table-cell code{background:0 0;border:0;padding:0;font-size:.82rem;font-weight:700}.mut__table-cell.is-here{border-color:var(--accent);box-shadow:0 0 0 1px var(--accent)}.mut__zoom-foot{margin-top:.7rem}.mut__tries{margin-left:auto;font-size:.82rem}@media (prefers-color-scheme:dark){.mut__zl-letter,.mut__key-letter{color:color-mix(in srgb, var(--base) 75%, #fff)}.mut__verdict--silent,.mut__verdict--whole,.mut__badge--silent,.mut__badge--whole{--vcol:#22a352}.mut__verdict--frameshift,.mut__badge--frameshift{--vcol:#8b5cf6}}@media (prefers-reduced-motion:reduce){.mut__bead,.mut__bead.mut__bead--ghost{animation:.3s both mut-fade}.mut__bead.is-changed:before{animation:none}.mut__bolt,.mut__burst{animation-duration:.9s}.mut__base-letter.is-zapped{animation:none}}@media (pointer:coarse){.mut .button,.mut .game__level,.mut .game__sound,.mut__code-btn,.mut__mode{min-height:2.75rem}}@media (width<=640px){.mut__mission{padding:.5rem .65rem .55rem;font-size:.92rem}.mut .mut__stage.is-intro{min-height:430px}.mut__stage-head{padding:.45rem .6rem 0}.mut__tag,.mut__codechip.is-optional,.mut__table-long{display:none}.mut .game__toast{padding:.5rem .9rem;font-size:.95rem}.mut__verdict{font-size:.9rem}.mut__headline{font-size:.95rem}.mut__step{display:none}.mut__map{margin:0 .6rem}.mut__legend{gap:.2rem .7rem;padding:.4rem .6rem .55rem}.mut__intro p{font-size:.9rem}.mut__zoom{padding:.55rem .6rem .6rem}.mut__zoom-main{gap:.35rem}.mut__zl{width:3.05rem;height:3.3rem}.mut__zoom-head{margin-bottom:.3rem}.mut__modes{margin-top:.45rem}.mut__actions{margin-top:.4rem}.mut__action-label{margin-bottom:.25rem}.mut__step{width:2.75rem}.mut__zoom-arrow{display:none}.mut__zoom-aa{flex:6rem;margin-left:.25rem}.mut__mini--lg{width:38px;height:38px;font-size:17px}.mut__mode{flex:1 1 0;min-width:0}.mut__modes{display:flex}}